Results 61 to 70 of about 1,651,428 (315)
Transonic Static Aeroelastic Numerical Analysis of Flexible Complex Configuration Wing
Shock and Vibration, 2021 Diamond back wing is subjected to large deformation while gliding, which significantly changes characteristics of the lift as well as the static stability.
Changrong Zhang +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Simulating Speed in Language: Contributions from vision, audition and action [PDF]
, 2015 Embodied theories propose that understanding meaning in language requires the mental simulation of entities being referred to. These mental simulations would make use of the same modality-specific systems involved in perceiving and acting upon such ...
Speed, LJ
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
High Speed Communication Techniques [PDF]
, 2019 This thesis deals with High Speed networks and their relevance in society. It explains the its technologies, performance and applications.The emergence of new high-speed networks challenges our view of distributed networking to great extent. The increase
Osadebamwen, Eghosa Okeoghene
core
International Journal of Chemical Engineering, 2018 The air-flow impacting based mechanochemical synthesis is an alternative strategy to traditional mechanochemical preparations, which has many advantages in terms of reaction temperature, preparation speed, and cleanness.
Yang Tao +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Aerodynamic forces on high speed multi-hulled marine vehicles [PDF]
, 2008 The need for high-speed high-payload craft has led to a considerable interest in vehicles capable of bridging the gap between conventional ships and aircraft. One such concept uses the forward motion of the craft to create aerodynamic forces on a wing-
Williams, A. G. W.
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source