Results 131 to 140 of about 380,525 (307)

Lifting and Transport of Martian Dust by the Ingenuity Helicopter Rotor Downwash as Observed by High-Speed Imaging From the Perseverance Rover. [PDF]

open access: yesJ Geophys Res Planets, 2022
Lemmon MT   +9 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

High-fidelity colour reproduction for high-dynamic-range imaging

open access: yes, 2010
The aim of this thesis is to develop a colour reproduction system for high-dynamic-range (HDR) imaging. Classical colour reproduction systems fail to reproduce HDR images because current characterisation methods and colour appearance models fail to ...
Kim, M.H.
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Development of a Full-Field Time-of-Flight Range Imaging System

open access: yes, 2008
A full-field, time-of-flight, image ranging system or 3D camera has been developed from a proof-of-principle to a working prototype stage, capable of determining the intensity and range for every pixel in a scene.
Payne, Andrew D.
core  

Towards high-speed computational scattered light imaging by introducing compressed sensing for optimized illumination

open access: yes
We propose the application of Compressed Sensing to Computational Scattered Light Imaging to decrease measurement time and data storage. Computational Scattered Light Imaging (ComSLI) determines three-dimensional fiber orientations and crossings in ...
Van Staalduine, Simon (author)   +5 more
core   +1 more source

Fibre-based imaging : new challenges

open access: yes, 2015
A novel minimally invasive micro-endoscopes utilizing disordered light within a standard multimode optical fibre have been introduced recently. The two most important limitations of this exciting technology are (i) the lack of bending flexibility ...
Straka, B.   +11 more
core   +1 more source

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