Results 111 to 120 of about 380,525 (307)

High-speed scanless entire bandwidth mid-infrared chemical imaging

open access: yes, 2022
Mid-infrared spectroscopy probes molecular vibrations to identify chemical species and functional groups. Therefore, mid-infrared hyperspectral imaging is one of the most powerful and promising candidates for chemical imaging using optical methods.
Yue Zhao (186573)   +5 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Label-free cell-cycle analysis by high-throughput quantitative phase time-stretch imaging flow cytometry

open access: yes, 2018
Biophysical properties of cells could complement and correlate biochemical markers to characterize a multitude of cellular states. Changes in cell size, dry mass and subcellular morphology, for instance, are relevant to cell-cycle progression which is ...
Wong, KKY, Lee, KCM, Mok, ATY, Tsia, KKM
core   +1 more source

High‐Speed Hyperspectral Imaging for Near Infrared Fluorescence and Environmental Monitoring

open access: yesAdvanced Science
Hyperspectral imaging captures both spectral and spatial information from a sample but is intrinsically slow. The near infrared (NIR, > 800 nm) is advantageous for imaging applications because it falls into the tissue transparency window and also ...
Jan Stegemann   +9 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Parallelized compressive spontaneous Raman imaging via SPAD arrays (Conference Presentation)

open access: yes
Compressive Raman imaging has emerged as a promising technique to speed up chemical imaging by compressing the data during acquisition. Yet, current scanning imaging speed is fundamentally limited by the sensors pixel dwell times of at best 1 µs.
Gentner, Clémence   +4 more
core   +1 more source

High speed perfusion imaging based on laser speckle fluctuations [PDF]

open access: yes, 2010
Noninvasive methods to visualize blood flow in tissue are important in the clinical environment. Most methods use dynamic speckles to measure the level of perfusion.
Draijer, Matthijs Johannes
core   +1 more source

High-speed, 3-dimensional, telecentric imaging

open access: yesOptics Express, 2006
The design, testing and operation of a system for telecentric 3-dimensional imaging of dynamic objects is presented. The simple system is capable of rapid electronic scanning of a single focal plane within a specimen or of simultaneous focusing on multiple planes whose depth and relative spacing within the specimen can be changed electronically ...
Slimane, Djidel   +3 more
openaire   +2 more sources

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