Results 101 to 110 of about 380,525 (307)

High-speed broadband CARS in the fingerprint region through supercontinuum generation in bulk media

, 2022
Spontaneous Raman spectroscopy is a powerful label-free and non-invasive imaging technique for mapping cells and tissues, delivering relevant biochemical information.
Ceconello C., De La Cadena A., Vanna R., Vernuccio F., Talone B., Bresci A., Cerullo G., Polli D.   +7 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

High-sensitivity high-speed compressive spectrometer for Raman imaging

, 2018
Compressive Raman is a recent framework that allows for large data compression of microspectroscopy during its measurement. Because of its inherent multiplexing architecture, it has shown imaging speeds considerably higher than conventional Raman ...
Herve Rigneault (5317358), Hilton B. de Aguiar (7180556), Fernando Soldevila (4732380), Benneth Sturm (17473896), Sylvain Gigan (1460524), Enrique Tajahuerce (3943310)   +5 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A novel high-speed digital imaging system for assessing vocal fold vibration

, 2014
Observing vocal fold vibration is essential when investigating the causes of hoarseness of voice and determining the appropriate treatment. However, in Japan, it is difficult at present to obtain commercial high-speed digital imaging (HSDI) systems for ...
Kaneko, Kenichi, Inoue, Masato, Takahashi, Haruo, Watanabe, Takeshi   +3 more
core  

High-speed-camera based on a CMOS active pixel sensor

, 2022
S.31 ...
Firla, H., Gick, S., Lauxtermann, S., Ernst, J., Schmölz, S., Bloß, H.   +5 more
core  

High Speed Pump-Probe Apparatus for Observation of Transitional Effects in Ultrafast Laser Micromachining Processes

Micromachines, 2015
A pump-probe experimental approach has been shown to be a very efficient tool for the observation and analysis of various laser matter interaction effects.
Ilya Alexeev, Johannes Heberle, Kristian Cvecek, Konstantin Yu. Nagulin, Michael Schmidt   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

High-speed multi-wavelength Fresnel diffraction imaging

, 2014
We demonstrate a compact lensless microscope which can capture video-rate phase contrast images of moving objects and allows numerical scanning of the focal distance after recording.
Eikema, K.S.E., Witte, S.M., Noom, D.W.E., Labordus, E., Boonzajer Flaes, D.E.   +4 more
core   +1 more source