Results 41 to 50 of about 1,415,532 (265)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Characterisation and modelling of structural bonding at high strain rate

EPJ Web of Conferences, 2012
These paper deals with the development of new bonded joint modelling for crash application. A new testing device has been set up on Split Hopkinson bars in order to identify adhesive’s properties in assemblies for high strain rate and for different ...
Lesueur D., Bennani B., Lauro F., Bourel B., Haugou G., Morin D.   +5 more
doaj   +1 more source

Physical nature of strain rate sensitivity of metals and alloys at high strain rates [PDF]

Journal of Physics: Conference Series, 2018
The role of instabilities of plastic flow at plastic deformation of various materials is one of the important cross-disciplinary problems which is equally important in physics, mechanics and material science. The strain rate sensitivities under slow and high strain rate conditions of loading have different physical nature.
Borodin, E. N., Gruzdkov, A. A., Mayer, A. E., Selyutina, N. S.   +3 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

High strain rate tensile and compressive effects in glassy polymers

EPJ Web of Conferences, 2012
Polymers are increasingly used in impact and complex high rate loading applications. Generally, the mechanical response of glassy polymers under high strain rates has been determined in compression.
Woodworth B.T., Siviour C.R., Jordan J.L.   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

High strain-rate response of additively manufactured light metal alloys

Materials & Design, 2022
Understanding the high strain-rate response of materials is essential in applications including aerospace, automotive, and defence. Structures of these applications are often subjected to dynamic loadings of high strain rates and need to mitigate the ...
Sami E. Alkhatib, Timothy B. Sercombe
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

High strain-rate deformation analysis of open-cell aluminium foam

Journal of Materials Research and Technology, 2023
This study investigated the high-strain rate mechanical properties of open-cell aluminium foam M-pore®. While previous research has examined the response of this type of foam under quasi-static and transitional dynamic loading conditions, there is a lack
Anja Mauko, Mustafa Sarıkaya, Mustafa Güden, Isabel Duarte, Matej Borovinšek, Matej Vesenjak, Zoran Ren   +6 more
doaj   +1 more source