Results 141 to 150 of about 4,094,018 (318)

Effect of welding defects on fatigue behavior of Ni-base superalloy GH4065A

Journal of Aeronautical Materials
The spot-welding defects of highly alloyed Ni-base superalloy GH4065A were investigated by using SEM and EBSD analysis methods. Effects of the welding defects on fatigue life and fracture behavior were studied by comparing thin plate samples with a ...
LI Linhan, ZHANG Ji, TIAN Chenggang, YANG Shanjie, SHEN Zhongmin, ZHANG Wenyun, ZHANG Beijiang   +6 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Thin-walled effect of microstructure of third-generation single crystal superalloy DD9

Cailiao gongcheng
The microstructure and thin-walled effect of different samples （double-wall ultra-cooling turbine blades， combined cooling turbine blades， investment casting thin-walled specimen， and round bar specimen） of the third-generation single crystal superalloy ...
YANG Wanpeng, LI Jiarong, LIU Shizhong, ZHAO Jinqian, WANG Xiaoguang, YANG Liang, WANG Rui, CHEN Qiao   +7 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

High temperature capable SiC Schottky diodes, based on buried grid design

, 2014
Electrical characteristics of 4H-SiC Schottky barrier diodes, based on buried grid design are presented. The diodes, rated to 1200V/10A and assembled into high temperature capable T0254 packages, have been tested and studied up to 250°C.
Hjort, T., Schöner, A., Kaplan, W., Zhang, A., Lim, Jang-Kwon,, Bakowski, M.   +5 more
core  

Development of Gasdynamic Probe for Total Temperature Measurement in gases [PDF]

, 2011
Total temperature measurement in exhaust stream of air breathing engines like Ramjet, Scramjet and Aircraft afterburners is a challenging task as the temperatures in such engine exhausts are above 2200K.
Srinivas, J, Baskaran, M, Manjunath, P, Sathiyamoorthy, K   +3 more
core  

The european SEEL (solutions for energy efficient lighting) project High temperature electronics for LED-lighting architectures

, 2022
S.193-206Due to superior properties in energy-efficiency and design freedom, the ".liberation of light" by LED- technology will draw more attention in future applications.
Ehrhardt, C., Reiners, T., Oelgeschlager, D., Habenicht, S., Willwohl, H., Walczyk, S., Fiederling, R., Vogl, M., Schug, J., Hutter, M., Mavinkurve, A., Blandin, J., Oppermann, H., Gehn, R., Funke, H.J., Gruber, D., Schumacher, O.   +16 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

A high temperature, high pressure reaction-screening apparatus

, 1985
This short note describes an apparatus that has been designed and constructed to allow assessment of the extent of chemical decomposition of fluids and fluid mixtures under high temperature, high pressure conditions. The apparatus is used to screen fluid
Bruno, T.J.; Hume, G.L.
core   +1 more source

Physical Mechanisms of “Shock Cooling” at the Molecular Fluid/Window Interface under Shock Loading

Gaoya wuli xuebao
The physical mechanism of “shock cooling” at the molecular fluid/window interface has troubled the shock wave physics community for many years and remains unsolved.
Kewei LI, Muhammad Sabeeh AKRAM, Lei YANG, Wenshuo YUAN, Fusheng LIU   +4 more
doaj   +1 more source