Results 121 to 130 of about 4,094,018 (318)

Effect of Y on Oxidation Behavior of Directionally Solidified Ni-Based Single-Crystal Superalloy

Chinese Journal of Mechanical Engineering
The effect of yttrium (Y) addition on the oxidation behavior of a Ni-based directionally solidified single-crystal superalloy is investigated in this study. Isothermal oxidation tests for samples with different levels of Y addition are conducted at 1100 °
Zihan Zhao, Kai Guan, Renjie Cui, Jianchao Qin, Zhaohui Huang   +4 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Luminescence at High Temperatures [PDF]

Proceedings of the National Academy of Sciences, 1920
E L, Nichols, D T, Wilbur
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A robust SOI gain-boosted operational amplifier targeting high temperature precision applications up to 300°C

, 2022
S.238-242Data acquisition and signal processing at elevated temperatures are facing various problems due to a wide temperature range operation, affecting the accuracy of the circuits' references and elementary building blocks.
Schmidt, A., Kappert, H., Marzouk, A.M., Kokozinski, R.   +3 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Pulsed-electromagnet EMAT for high temperature applications [PDF]

This thesis is concerned with the design and implementation of an Electromagnetic Acoustic Transducer (EMAT) intended for high temperature ultrasonic applications; which benefits from a novel approach using a pulsed current electromagnet (PE) and a ...
Hernández Valle, José Francisco
core  

Fe nano-particle coatings for high temperature wear resistance

, 2011
Oxidational wear continues to present an economic challenge for the replacement of components subject to high temperature fretting and sliding contacts in applications such as gas turbine engines.
S.R. Saranu, A.H. Kean, Wood, R.J.K., Robert Wood, Walker, J.C., John Christopher Walker, A. H. Kean, Saranu, S.R., J.C. Walker, S. R. Saranu, R. J. K. Wood, Kean, A.H., R.J.K. Wood   +12 more
core   +1 more source

Effect of AlF3·3H2O addition on microstructure and properties of ceramic shell for investment casting

Cailiao gongcheng
Using fused corundum powder as raw material， silica sol as a binder， and aluminum fluoride trihydrate as mullite phase conversion promoter， the slurry composition of the ceramic shell for directional solidification molding of turbine blades was designed，
LI Zhihui, ZHAO Yanjie, CHEN Xiaoyan, QI Chengkang, LAI Junhua, LU Liangliang, LI Fei   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source