Results 121 to 130 of about 7,910,907 (308)

Luminescence at High Temperatures [PDF]

open access: yesProceedings of the National Academy of Sciences, 1920
E L, Nichols, D T, Wilbur
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Structural application of high strength, high temperature ceramics [PDF]

open access: yes, 1982
The operation of rocket engine turbine pumps is limited by the temperature restrictions of metallic components used in the systems. Mechanical strength and stability of these metallic components decrease drastically at elevated temperatures.
Hall, W. B.
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

High-temperature, long-life thyratron [PDF]

open access: yes, 1972
Thallium and xenon filled thyratron was developed that operates at tube envelope temperatures up to 750 C. This tube performs at peak voltage ratings of 2000 V forward and reverse and at an average current rating of 15 A for up to 11,000 ...
Baum, E. A., Jones, N. D.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Effect of AlF3·3H2O addition on microstructure and properties of ceramic shell for investment casting

open access: yesCailiao gongcheng
Using fused corundum powder as raw material, silica sol as a binder, and aluminum fluoride trihydrate as mullite phase conversion promoter, the slurry composition of the ceramic shell for directional solidification molding of turbine blades was designed,
LI Zhihui   +6 more
doaj   +1 more source

Gallium phosphide high temperature diodes [PDF]

open access: yes, 1981
High temperature (300 C) diodes for geothermal and other energy applications were developed. A comparison of reverse leakage currents of Si, GaAs, and GaP was made. Diodes made from GaP should be usable to 500 C.
Chaffin, R. J., Dawson, L. R.
core   +1 more source

Fatigue at High Temperature

open access: yes, 1973
This report was prepared as the keynote address given at the 1972 Symposium on Fatigue at Elevated Temperatures at the University of Connecticut, 18–23 June, 1972. It describes the high-temperature fatigue problem as a failure process in a notch in some structure involving nucleation and early growth at the notch root, high-strain crack propagation ...
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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