Results 111 to 120 of about 15,635,515 (278)

Bond Strength Degradation for Prestressed Steel and Carbon FRP Bars in High-Performance Self-Consolidating Concrete at Elevated Temperatures and in Fire [PDF]

open access: yes, 2010
Novel structures are emerging utilizing high performance, self-consolidating, fibre-reinforced concrete (HPSCC) reinforced with high-strength, lightweight, and non-corroding prestressed reinforcement.
Hugi, E.   +4 more
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Chiral current at high temperatures

open access: yesPhysical Review D, 1994
The BP-FTW effective action is a good laboratory to study the nature of chiral symmetry at high $T$. It is invariant under a new Noether charge, $\Qbeta$. By explicit quantization, performed to order $\Tprime$ we show that the thermal vacuum is annihilated by $\Qbeta$, so that the new chiral symmetry is not broken spontaneously at high $T$.
openaire   +3 more sources

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Corrigendum: Ontologies and databases on thermophysical properties of nuclear reactor materials (NUCET 5(2): pp. 145–153, 2019) [PDF]

open access: yesNuclear Energy and Technology, 2023
Igor Chusov   +6 more
doaj   +3 more sources

Growth of Chlorella vulgaris Under Atmospheric CO2 in Lab-Scale Photobioreactors: Effects of Aeration Rate and Growth Model Comparison

open access: yesBioengineering
This study presents the results of an experimental investigation on the growth of the microalga Chlorella vulgaris in laboratory-scale photobioreactors under different aeration intensities: 0.25–3.25 vvm (vessel volumes per minute).
Vadim A. Pavlov   +3 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

High temperature indentation of WC/Co hardmetals

open access: yes, 2013
WC/Co is the material of choice for most high wear applications such as hot forming operations, drilling, cutting, machining and wire drawing due to its superior wear properties.
Zunega, Jonee Christine
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

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