Results 91 to 100 of about 2,848,674 (305)

Ab initio inspection of thermophysical experiments for molybdenum near melting

open access: yesAIP Advances, 2018
We present quantum molecular dynamics calculations of thermophysical properties of solid and liquid molybdenum in the vicinity of melting. Detailed analysis of available experimental isobaric expansion data and extensive comparison over a wide set of ...
D. V. Minakov   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Meson correlation functions at high temperatures

open access: yes, 2005
We present preliminary results for the correlation- and spectral functions of different meson channels on the lattice. The main focus lies on gaining control over cut-off as well as on the finite-volume effects.
Datta, S.   +4 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Incipient order in the t-J model at high temperatures

open access: yes, 2007
We analyze the high-temperature behavior of the susceptibilities towards a number of possible ordered states in the t-J-V model using the high-temperature series expansion.
J. G. A. Baker   +9 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

HIGH TEMPERATURE SYMMETRY NONRESTORATION [PDF]

open access: yesCOSMO-99, 2000
This is a short review on the subject of symmetry nonrestoration at high temperature. Special emphasis is put on experimental discoveries and different theoretical mechanisms. At the end, possible cosmological applications are briefly mentioned.
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The Influence of External Radiation on the Emission Properties of H- and He-like Argon Ions in High Temperature Plasma

open access: yesAtoms
In the present work, the influence of external X-ray radiation on the kinetics of multicharged ions in high-temperature plasma is investigated. A generalized diagnostic approach is proposed for the electron density and temperature measurements of photo ...
Roman K. Kulikov   +2 more
doaj   +1 more source

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