Results 91 to 100 of about 15,635,515 (278)
New Journal of Physics, 2013 A mathematical simulation of a dust particle's behavior in the electrodynamic linear quadrupole trap with closing end electrodes allowed us to reveal several features of the phenomena.
L M Vasilyak +7 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Thermal degradation of polymers at high temperatures
, 1959 Work on thermal degradation of polymers has previously been carried out at temperatures up to about 500 °C. In the present work the range has been extended to 850 °C. Polystyrene was pyrolyzed in a vacuum and also in helium at atmospheric pressure at 362
Madorsky, Samuel L.; Straus, Sidney
core +1 more source
BioengineeringMicroalgae of the genus Chlorella are widely used in biotechnology for biofuel production, wastewater treatment, and biomass generation. This study examined the effect of initial biomass concentration on the growth kinetics of Chlorella vulgaris ...
Vadim A. Pavlov +4 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
High Pressure Enhances the Growth Rate of the Thermophilic Archaebacterium Methanococcus thermolithotrophicus without Extending Its Temperature Range [PDF]
, 1988 Temperature and hydrostatic pressure are essential in determining the assemblage of species in their specific biotopes. To evaluate the effect of high pressure on the range of viability of thermophiles, the pressure and temperature dependence of the ...
Lüdemann, Hans-Dietrich +4 more
core +1 more source
Growth of Limnospira platensis Under Elevated CO2 with the Addition of Sodium Selenite
PlantsCultivation of L. platensis under elevated CO2 ensures CO2 biofixation, while adding Na2SeO3 to the culture medium, produces valuable Se-enriched biomass.
Anatoly V. Grigorenko +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Synthesis of methanol from gaseous products of pyrolysis of sewage sludge
Тонкие химические технологииObjectives. To study the influence of compositional variability (different ash and organic matter contents) of sewage sludge on the characteristics of synthesis gas (syngas) and to determine the yield of products in the entire chain of conversion of ...
O. M. Larina +3 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source