Results 71 to 80 of about 15,635,515 (278)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Modelling of cyclic behaviour of Haynes 282 at elevated temperatures

open access: yes, 2014
In this paper, the cyclic modelling of Haynes 282 is investigated for a range of elevated temperatures. A calibration of a plastic model including cyclic hardening/softening has been performed and a temperature dependence for the material parameters has ...
Brommesson, Rebecka   +3 more
core   +1 more source

Theoretical and Experimental Investigations of Substantiating Technologies for Carbon Materials Production from Natural Gas

open access: yesEurasian Chemico-Technological Journal, 2003
The results of theoretical and experimental investigations on methane pyrolysis with infiltration through a heated porous matrix generated from various carbon materials are presented. The features of mathematical models, kinetic relationships of process
L.B. Director   +5 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Comparative Economic Analysis for Different Types of Electric Vehicles

open access: yesInternational Journal of Sustainable Energy Planning and Management, 2020
This study is dedicated to comparing the levelized operating costs of various types of power units and energy carriers for electric vehicles: battery systems, hydrogen-air fuel cells, and aluminum-air electrochemical generators.
Evgeny Buzoverov, Andrey Zhuk
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Revising midlatitude summer temperatures back to A.D. 600 based on a wood density network [PDF]

open access: yes, 2015
Annually resolved and millennium-long reconstructions of large-scale temperature variability are primarily composed of tree ring width (TRW) chronologies.
Esper, J.   +20 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Ultra-low electron temperatures in nanostructured samples [PDF]

open access: yes, 2015
Nanostructured samples, be it semiconducting or metallic ones, have received considerable experimental and theoretical attention due to the manifold of possibilities to investigate fundamental physics. Not only are they viable candidates for realizations
Casparis, Lucas
core   +1 more source

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