Results 81 to 90 of about 1,227,725 (294)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

MINING CONCISE REPRESENTATIONS OF FREQUENT HIGH-UTILITY OCCUPANCY ITEMSETS USING GENERATOR PATTERNS

Tạp chí Khoa học Đại học Đà Lạt
A current trend in data mining is the discovery of frequent high-utility occupancy itemsets (FHUOIs) in quantitative databases. These itemsets capture user preferences and significantly contribute to transaction utility, making them valuable for real ...
Van Hai Duong, Minh Tien Hoang, Chi Tin Truong   +2 more
doaj   +1 more source

LUIM: New Low-Utility Itemset Mining Framework

IEEE Access, 2019
High-utility itemset mining (HUIM), which is the detection of high-utility itemsets (HUIs) in a transactional database, provides the decision maker with greater flexibility to exploit item utilities, such as quantity and profits, to extract remarkable ...
Naji Alhusaini, Saleem Karmoshi, Ammar Hawbani, Li Jing, Abdullah Alhusaini, Yaser Al-sharabi   +5 more
doaj   +1 more source

Identifying Attrition Phases in Survey Data: Applicability and Assessment Study [PDF]

, 2019
Background: Although Web-based questionnaires are an efficient, increasingly popular mode of data collection, their utility is often challenged by high participant dropout. Researchers can gain insight into potential causes of high participant dropout by
Hochheimer, Camille J., Krist, Alex H., Mukhopadhyay, Nitai, Perera, Robert A., Sabo, Roy T.   +4 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Privacy Preserving Utility Mining: A Survey

, 2018
In big data era, the collected data usually contains rich information and hidden knowledge. Utility-oriented pattern mining and analytics have shown a powerful ability to explore these ubiquitous data, which may be collected from various fields and ...
Chao, Han-Chieh, Gan, Wensheng, Lin, Jerry Chun-Wei, Wang, Shyue-Liang, Yu, Philip S.   +4 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source