Results 81 to 90 of about 1,895,501 (280)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

MINING CONCISE REPRESENTATIONS OF FREQUENT HIGH-UTILITY OCCUPANCY ITEMSETS USING GENERATOR PATTERNS

open access: yesTạp chí Khoa học Đại học Đà Lạt
A current trend in data mining is the discovery of frequent high-utility occupancy itemsets (FHUOIs) in quantitative databases. These itemsets capture user preferences and significantly contribute to transaction utility, making them valuable for real ...
Van Hai Duong   +2 more
doaj   +1 more source

LUIM: New Low-Utility Itemset Mining Framework

open access: yesIEEE Access, 2019
High-utility itemset mining (HUIM), which is the detection of high-utility itemsets (HUIs) in a transactional database, provides the decision maker with greater flexibility to exploit item utilities, such as quantity and profits, to extract remarkable ...
Naji Alhusaini   +5 more
doaj   +1 more source

Approximate high utility itemset mining in noisy environments

open access: yes, 2021
High utility pattern mining has been proposed to overcome the limitations of frequent pattern mining which cannot reflect the unique profits of items. High utility pattern mining has been actively conducted because it can find more valuable patterns than
Bay Vo   +6 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Extracting Potentially High Profit Product Feature Groups by Using High Utility Pattern Mining and Aspect Based Sentiment Analysis

open access: yes, 2019
As a subproblem of sentiment analysis topic, aspect based sentiment analysis aims to extract distinct opinions for different aspects of a case in a given text.
Alkan, Öznur   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A parallel declarative framework for mining high utility itemsets

open access: yes, 2022
International audienceOne of the most active research topics in data mining is pattern discovery involving the well-known task of enumerating interesting patterns from databases.
Hidouri, Amel   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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