Results 91 to 100 of about 1,227,725 (294)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
An Incremental High-Utility Mining Algorithm with Transaction Insertion
Association-rule mining is commonly used to discover useful and meaningful patterns from a very large database. It only considers the occurrence frequencies of items to reveal the relationships among itemsets.
Jerry Chun-Wei Lin +3 more
doaj +1 more source
Assessing Data Usefulness for Failure Analysis in Anonymized System Logs
System logs are a valuable source of information for the analysis and understanding of systems behavior for the purpose of improving their performance. Such logs contain various types of information, including sensitive information.
Ciorba, Florina M., Ghiasvand, Siavash
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The effect of pension rules on retirement monetary incentives with an application to pension reforms in Spain [PDF]
In this work we theoretically disentangle the effects of pension provisions on a variety of financial incentives to retirement, trying to reconcile them with some key Spanish retirement patterns.
Jiménez-Martín, Sergi +1 more
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Fast Single Pbase Algoritbm for Utility Mining in Big Data
Most of the latest works on utility mining generates a huge number of candidates in dealing with big data,which suffers from the scalability issue.Some work does not generate candidates,but suffers from the efficiency issue due to lack of strong pruning ...
Junqiang Liu +3 more
doaj +2 more sources
Objectives Identification of clinically significant irritability in preschool age is important to implement effective interventions. However, varying informant and measurement methods display distinct patterns.
Alyssa J. Parker +6 more
doaj +1 more source

