Results 121 to 130 of about 2,220,727 (242)

Lifestyle Medicine: A Foundational Framework for High-Value Care. [PDF]

Am J Lifestyle Med
Patel P.
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Corrigendum to “Design and methods of an adaptive trial to test comparative effectiveness of readmission reduction approaches following infection and sepsis hospitalizations (ACCOMPLISH)” [Contemp. Clinic. Trials Commun. 46 (2025) 101504]

Contemporary Clinical Trials Communications
Kristin Mayes, Victor B. Talisa, Adelina Malito, Florian B. Mayr, Kelly Williams, Kalpana Char, Richard Wadas, Elizabeth Lorenzi, Kert Viele, Rana Awdish, Derek C. Angus, Chung-Chou Ho Chang, Sachin Yende   +12 more
doaj   +1 more source

Reducing Laboratory Testing and Blood Draws in the Newborn Nursery to Increase High-value Care. [PDF]

Pediatr Qual Saf
Foster LZ, Natale L, Lukaszewicz J, Kleynerman M, Colameco J, Weckesser J, Ortale C, Haines E.   +7 more
europepmc   +1 more source

The paediatrician as a leader: A resident educational intervention for high-value care. [PDF]

Paediatr Child Health, 2020
Foulds JL, Forbes KL.
europepmc   +1 more source

Patient-centered high-value integrated care

Asian Biomedicine, 2022
openaire   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

High-Value Care Inclusion in the Preclinical and Clinical Years of Medical School: A Narrative Review and Descriptive Experience at a Single Institution. [PDF]

Cureus
Storm LK, Salvemini JD, Shields ML, Harris SK, Roux JA, Couey CC, Yang J, Doherty CG, Overton JS, Jeter JB.   +9 more
europepmc   +1 more source

Call for Papers: Value-Based Care and High-Value Care

The Permanente Journal, 2023
openaire   +1 more source