Results 131 to 140 of about 2,220,727 (242)

Teaching High-Value Care on Rounds [PDF]

open access: yesJAMA Internal Medicine, 2016
Rachel J, Stern, Anna L, Parks
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Lifestyle Medicine as a Framework for High-Value Care: A Position Statement From the American College of Lifestyle Medicine. [PDF]

open access: yesAm J Lifestyle Med
Marshall S   +14 more
europepmc   +1 more source

Demonstration of high value care to improve oral health of a remote Indigenous community in Australia. [PDF]

open access: yesHealth Qual Life Outcomes, 2020
Kularatna S   +5 more
europepmc   +1 more source

High-value care through better care coordination? [PDF]

open access: yesInternational Journal of Care Coordination, 2017
openaire   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

High-value care for older adults with complex care needs: Leveraging nurses as innovators. [PDF]

open access: yesNurs Outlook, 2020
Demiris G   +5 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

In Reply to Dimitroyannis. [PDF]

open access: yesPract Radiat Oncol
Saulsberry L, Huo D.
europepmc   +1 more source

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