Results 201 to 210 of about 2,220,727 (242)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Association of Standardization of Continuous Renal Replacement Therapy and High-Value Care: An Evidence-Based Approach.

JAMA Intern Med, 2018
Tseng J, Halbert RJ, Minissian N, Rodriguez H, Barathan S, Hain P, Alban RF.   +6 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

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Providing High-Value, Cost-Conscious Care

Annals of Internal Medicine, 2011
The Accreditation Council for Graduate MedicalEducation’s system-based practice competency, discussed in Wein-berger’s article (1), is more than teaching quality improvement andbeing a team player. “...Residents must be able to utilize resourceswithin the system to provide excellent patient care by...demon-strating cost effective resource allocation ...
Carlos O, Weiss, Maia, Holden, Matthew, McNabney   +2 more
  +16 more sources

High-Value Care Outcomes of Meningiomas

Neurosurgery Clinics of North America, 2023
High-value health care has become a widely researched topic within neurosurgery. The concept of "high-value" care involves optimizing resource expenditures relative to patient outcomes, and therefore, high-value care research within neurosurgery has involved identifying prognostic factors for outcomes such as hospital length of stay, discharge ...
Adrian E, Jimenez, Debraj, Mukherjee
openaire   +2 more sources

Implementing High-Value Care

Southern Medical Journal, 2015
Our objectives were to assess physician knowledge of costs of products, tests, and services commonly used by obstetrician/gynecologists (OB/GYNs) and identify those items that could be eliminated without decreasing quality of care by performing a prospective observational pilot study.An anonymous electronic survey was distributed to 70 OB/GYN providers
Lauren D, Demosthenes, Andrew S, Lane, Dawn W, Blackhurst   +2 more
openaire   +2 more sources

Delivering high-value breast care

Breast Global Journal, 2023
Abstract Focusing only on survival and recurrence outcomes can lead to breast cancer overtreatment, high costs, and poor patient experience. Providing care through the lens of the patient improves value in breast cancer treatment.
Jill R Dietz, Sneha Joshi, Ankush Dewle
openaire   +1 more source

High‐value care for senior medical students

The Clinical Teacher, 2020
Background Physicians have an opportunity to address rising health care costs by optimising resource use. Recent research suggests that regional spending patterns influence student engagement with high‐ and low‐value behaviours, revealing that these behaviours may be adopted early in ...
Mary Lacy, Leonard Noronha
openaire   +2 more sources