Results 111 to 120 of about 8,004 (311)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Partial Discharge Location within a Transformer Winding using Principal Component Analysis
, 2011 Partial discharge (PD) may occur in a transformer winding due to ageing processes, operational over stressing or defects introduced during manufacture. The presence of PD does not necessarily indicate imminent failure of the transformer but it will lead ...
Abd Rahman, M S, Hao, L, Lewin, P L
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
EnergiesIt is of the utmost importance to accurately solve the transformer temperature field, as it governs the overall performance and operational stability of the transformer.
Jianwei Han +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Simulation of a transformer winding for partial discharge propagation studies
, 2002 A simulation model of a continuous disc type 6.6 kV transformer winding was used to study the propagation behaviour of partial discharge (PD) pulses. The model based on multi-conductor transmission line theory uses a single turn as a circuit element with
Darwin, A. +4 more
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Wide Voltage Resonant Converter Using a Variable Winding Turns Ratio
, 2020 This paper presents a inductor–inductor–capacitor (LLC) resonant converter with variable winding turns to achieve wide voltage operation (100–400 V) and realize soft switching operation over the entire load range.
Bor-Ren Lin, Chu-Xian Dai
core +1 more source
Voltage Distribution on Transformer Windings Subjected to Lightning Strike Using State-Space Method
Applied SciencesTransient analysis in power systems is essential for identifying deficiencies in the system, as well as for the protection and design of equipment. Transients can arise from natural events or network operations; in either case, they have the potential to
İlker Arı, Mehmet Salih Mamiş
doaj +1 more source
Transformer sound level caused by core magnetostriction and winding stress displacement variation
AIP Advances, 2017 Magnetostriction caused by the exciting variation of the magnetic core and the current conducted by the winding wired to the core has a significant result impact on a power transformer.
Chang-Hung Hsu +5 more
doaj +1 more source