Results 101 to 110 of about 322,076 (276)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Shehu Transform and Applications to Caputo-Fractional Differential Equations

International Journal of Analysis and Applications, 2019
In this manuscript we establish the expressions of the Shehu transform for fractional Riemann-Liouville and Caputo operators. With the help of this new integral transform we solve higher order fractional differential equations in the Caputo sense.
Rachid Belgacem, Dumitru Baleanu, Ahmed Bokhari   +2 more
doaj   +2 more sources

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Existence and Approximate Controllability for Higher-Order Hilfer Fractional Evolution Equations via Fixed-Point and Sequence Approaches

Mathematics
This study addresses the existence and approximate controllability of a type of higher-order Hilfer fractional evolution differential (HOHFED) system with time delays in Banach spaces. Using the properties of the Mittag–Leffler function, cosine families,
Marimuthu Mohan Raja, Chan-Ho Han, Kalyana Chakravarthy Veluvolu   +2 more
doaj   +1 more source

An inverse scattering formalism for higher-order differential operators

Journal of Mathematical Analysis and Applications, 1986
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

The higher order differential operators in direct sum spaces

Journal of Differential Equations, 1990
The author studies two ordinary differential operators \[ M_ iy=p_{0i}y^{(n)}+p_{1i}y^{(n-1)}+...+p_{ni}y,\quad i=1,2, \] given on intervals \(I_ 1=[a,b]\) and \(I_ 2=[c,d]\) respectively, \(- \infty \leq ...
openaire   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

A second regularized trace formula for a higher order differential operator

Mathematical Methods in the Applied Sciences, 2020
In this paper, we obtain a second regularized trace formula onL2([0, π]; H)for a higher order self‐adjoint differential operator with unbounded operator‐valued coefficient, whereHis a separable Hilbert space.
openaire   +4 more sources