Results 31 to 40 of about 3,855 (243)

Approximated Risk Probability of having Atherosclerosis, Cardiovascular Disease, and Stroke during the COVID-19 Period Using the Pre-COVID Period’S Dataset as Baseline of Calculations and Higher-Order Perturbation Equations from Quantum Mechanics Based on GH-Method: Math-Physical Medicine (No. 465)

Advances in Bioengineering and Biomedical Science Research, 2022
This paper describes the author’s assessment on his risk probability percentage of having atherosclerosis, cardiovascular disease (CVD), and stroke. During the 7-quarters of the COVID-19 period from 2/5/2020 to 11/4/2021, he utilized his earlier 7-quarters data from 5/5/2018 to 2/4/2020 or the “pre-COVID period” and higher-order perturbation theory ...
openaire   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Double neutral-current corrections to NLO electroweak leptonic cross sections

Journal of High Energy Physics
We present a method for improving next-to-leading order electroweak (EW) predictions for lepton-scattering processes by consistently including double neutral-current corrections arising from vector-boson-fusion topologies, which are formally of higher ...
Stefano Frixione, Fabio Maltoni, Davide Pagani, Marco Zaro   +3 more
doaj   +1 more source

Analysis of double-J/ψ production in Z decay at next-to-leading-order QCD accuracy

Journal of High Energy Physics, 2023
In this article, we study in detail the double-J/ψ yield through Z decay at the next-to-leading-order (NLO) QCD accuracy within the nonrelativistic QCD factorization. At the tree level, the pure QCD diagrams predict a branching ratio of B Z → J / ψ + J /
Cong Li, Zhan Sun, Gui-Yuan Zhang
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Angular phase-space integrals with four denominators through Mellin-Barnes

Journal of High Energy Physics
We compute four-denominator angular phase-space integrals using the Mellin-Barnes (MB) technique in dimensional regularisation. Independent of the scattering process, an angular integral can be categorised based on the nature of the momenta appearing in ...
Taushif Ahmed, Syed Mehedi Hasan, Andreas Rapakoulias   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source