Results 91 to 100 of about 2,566,078 (299)
Complexity Hierarchies and Higher-order Cons-free Term Rewriting
Logical Methods in Computer Science, 2017 Constructor rewriting systems are said to be cons-free if, roughly, constructor terms in the right-hand sides of rules are subterms of the left-hand sides; the computational intuition is that rules cannot build new data structures. In programming language research, cons-free languages have been used to characterize hierarchies of computational ...
Kop, Cynthia Louisa Martina +1 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Thermodynamics of Electrolytes.: V. Effects of Higher-Order Electrostatic Terms [PDF]
Journal of Solution Chemistry, 1975 The contribution of higher-order electrostatic terms (beyond the Debye-Huckel approximation) to the thermodynamic properties of mixed and pure electrolytes is investigated. It is found that these effects are important for cases of unsymmetrical mixing, especially when one ion has a charge of three units or more.
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Higher order corrections to multijet production in e(^+)e(^-) annihilation [PDF]
, 1998 The analysis of hadronic events in high-energy electron-positron annihilation often relies upon the clustering of individual hadrons into energetic jets.
Campbell, John M.
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Second-order approximation for adaptive regression estimators. [PDF]
We derive asymptotic expansions for semiparametric adaptive regression estimators. In particular, we derive the asymptotic distribution of the second-order effect of an adaptive estimator in a linear regression whose error density is of unknown ...
Linton, Oliver, Xiao, Zhijie
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Global Dynamics of a Higher Order Difference Equation with Quadratic Term
Journal of Applied Mathematics and Computing, 2020 In this paper, we investigate the dynamics of following higher order difference equation x_{n+1}=A+B((x_{n})/(x_{n-m}²)) with A,B and initial conditions are positive numbers. Especially we study the boundedness, periodicity, global asymptotically stability and rate of convergence of related higher order difference equations.
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FEBS Letters, EarlyView.The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
Efficient Frontier for Robust Higher-order Moment Portfolio Selection [PDF]
This article proposes a non-parametric portfolio selection criterion for the static asset allocation problem in a robust higher-moment framework. Adopting the Shortage Function approach, we generalize the multi-objective optimization technique in a four ...
Emmanuel Jurczenko +2 more
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