Results 71 to 80 of about 7,930,128 (288)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Higher order terms in the inflaton potential and the lower bound on the tensor to scalar ratio r
, 2009 The MCMC analysis of the CMB+LSS data in the context of the Ginsburg-Landau approach to inflation indicated that the fourth degree double--well inflaton potential best fits the present CMB and LSS data.
Alabidi +52 more
core +3 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
, 2006 The spontaneous breakdown of SO(10) symmetry of the IIB matrix model has been studied by using the improved mean field approximation (IMFA). In this report, the eighth-order contribution to the improved perturbative series is obtained, which involves ...
Anagnostopoulos +14 more
core +1 more source
Geometric Second Order Field Equations for General Tensor Gauge Fields [PDF]
, 2003 Higher spin tensor gauge fields have natural gauge-invariant field equations written in terms of generalised curvatures, but these are typically of higher than second order in derivatives.
+37 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Stability of the Weak Skyrmions
, 1993 We consider a set of gauge invariant terms in higher order effective Lagrangians of the strongly interacting scalar of the electroweak theory. The terms are introduced in the framework of the hidden gauge symmetry formalism. The usual gauge term is known
A. Dobado +21 more
core +1 more source
Bounded Higher-order Unification using Regular Terms
EPiC Series in Computing, 2018 We present an algorithm for the bounded unification of higher-order terms.The algorithm extends G. P. Huet's pre-unification algorithm with rules for the generation and folding of regular terms.The concise form of the algorithm allows the reuse of the pre-unification correctness proof.
openaire +2 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source