Results 81 to 90 of about 2,566,078 (299)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Nested Term Graphs (Work In Progress) [PDF]
Electronic Proceedings in Theoretical Computer Science, 2015 We report on work in progress on 'nested term graphs' for formalizing higher-order terms (e.g. finite or infinite lambda-terms), including those expressing recursion (e.g. terms in the lambda-calculus with letrec).
Clemens Grabmayer, Vincent van Oostrom
doaj +1 more source
The Skyrme model and higher order terms
Physics Letters B, 1990 Abstract We generalize the Skyrme lagrangian by considering a set of higher order terms in derivatives of the pion field (up to order twelve) using a systematic approach. We then consider a combination of those terms which preserves the equation for the chiral angle as a second-degree differential equation.
openaire +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Multi-parameter approximation of stress field in a cracked specimen using purpose-built Java applications [PDF]
Fracture and Structural Integrity, 2015 A quality of multi-parameter approximation of the stress and displacement fields around a crack tip in a non-brittle material test specimen is studied in the paper.
V. Veselý +5 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
An efficient solver for solving chemical kinetic equations using higher order block backward differentiation formula [PDF]
, 2019 In this paper, an efficient solver known as higher order block backward differentiation formula (HOBBDF) is applied to chemical kinetic equations. In order to prove the applicability of this higher order solver, the chemical kinetic ordinary differential
Asnor, Asma Izzati +2 more
core
A Transfinite Knuth-Bendix Order for Lambda-Free Higher-Order Terms [PDF]
, 2017 International audienceWe generalize the Knuth-Bendix order (KBO) to higher-order terms without λ-abstraction. The restriction of this new order to first-order terms coincides with the traditional KBO.
Becker, H. +14 more
core +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source