Results 91 to 100 of about 20,457,382 (398)

Who is missing from higher education? [PDF]

, 2008
This paper discusses the difficulties of establishing a clear count of UK higher education students in terms of the categories used for widening participation, such as occupational background or ethnicity.
Gorard, Stephen
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Mechanical modelling and simulation of thrust force in drilling process in GFRP composite laminates: A novel system dynamics approach

Cogent Engineering, 2019
Drilling is a salient machining process employed in assembling the components and structures made from polymer composites. Influence of various drilling process parameters on the drilling process has been identified and controlled to maintain the ...
B. R. N. Murthy, Vijay G.S, S. Narayan, Nithesh Naik, Nilakshman Sooriyaperakasam, Aravind Karthik, Revati Borkhade   +6 more
doaj   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Psychosocial Burden Among Informal Caregivers of Adult Cancer Patients Attending a Tertiary Care Cancer Center in Coastal South India

SAGE Open, 2019
Cancer is the most dreaded and chronic disease with its treatment lasting almost lifelong with an uncertainty of cure. This not only adversely affects the quality of life among patients but also poses a psychosocial burden among family members ...
Bhaskaran Unnikrishnan, Priya Rathi, P. U. Prakash Saxena, Apoorva Aggarwal, Shashank Shekhar, Sarthak Bansal, B. Venkat Naidu, Sarath Menon   +7 more
doaj   +1 more source

Higher education stimulating creative enterprise [PDF]

, 2011
This report summarises the research undertaken by the Business & Community School at the University for the Creative Arts (UCA), analysing ways that higher ediucation (HEIs) can support, and indeed stimulate, the creative economy.
Campbell, Frances, Ely, Philip
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Results of implementation of social rehabilitation technologies for people with lower extremity diseases/injuries

Social Welfare: Interdisciplinary Approach, 2013
People with lower extremity diseases/injuries have limited mobility that affects their participation in socio-economic processes, including integration into the labour market. It is one of the risk groups that are exposed to the risk of social exclusion,
Svetlana Usca, Velta Lubkina, Aivars Kaupuzs, Lorita Rizakova   +3 more
doaj   +1 more source

Explaining Demand for Higher Education [PDF]

, 2012
Recognizing the crucial role of higher education for the development of nations and individuals, many countries have recently established ambitious targets for the percentage of graduates in their population by 2020.
Oliveira, Manuela, Vieira, Carlos, Vieira, Isabel   +2 more
core  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source