Results 91 to 100 of about 7,501,853 (298)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Chatting or Cheating – Test of a First-Rate Intelligence?

open access: yesJournal of Ethics in Higher Education
The emergence of Large Language Models (LLMs) has significantly influenced the landscape of Higher Education, with their adoption by students and educators escalating rapidly since OpenAI introduced ChatGPT in November 2022.
Olivia Wilson   +2 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Progression of apprentices to higher education [PDF]

open access: yes, 2013
This report presents the findings of research undertaken for the Department for Business, Innovation and Skills (BIS) into the progression to higher education of advanced level apprentices over the past seven years.
Joslin, Hugh, Smith, Sharon
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Evaluation of mean glandular dose in relation to breast density in digital mammography

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine
Background Mammography is considered an ideal tool for breast cancer screening due to its proven effectiveness, which has led to its widespread use as the primary imaging modality for early detection.
Fatemeh Amiri   +7 more
doaj   +1 more source

Higher education: Distance education and mercantilization of higher education

open access: yes, 2019
Este artigo objetiva comparar, no nível do ensino superior, a educação a distância ministrada pelos conglomerados educacionais com a EaD veiculada, sobretudo, pelas universidades públicas, PUCs, e instituições ligadas à Rede Federal de Educação Profissional Científica e Tecnológica (RFEPCT).
Oliveira, Maria Auxiliadora Monteiro   +1 more
openaire   +1 more source

E-book readers in higher education [PDF]

open access: yes, 2003
Ebook readers have received a mixed press, with some hailing them as the future of reading and others believing that they will never be popular. The study outlined here aims to understand the attitudes of, and issues of importance to, lecturers in UK ...
Wilson, R.
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Green synthesis and multifaceted applications: challenges and innovations in carbon dot nanocomposites

open access: yesDiscover Nano
This paper describes the potential of carbon dot nanocomposites (CDs) synthesized from waste materials by top-down and bottom-up state-of-the-art approaches.
S. Varadharajan   +4 more
doaj   +1 more source

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