Results 111 to 120 of about 1,265,236 (304)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Generalizability of empirical correlations for predicting higher heating values of biomass

Energy Sources, Part A: Recovery, Utilization, and Environmental Effects
Designing efficient biomass energy systems requires a thorough understanding of the physicochemical, thermodynamic, and physical properties of biomass. One crucial parameter in assessing biomass energy potential is the higher heating value (HHV), which quantifies its energy content.
Mahmut Daskin, Ahmet Erdoğan, Fatih Güleç, Jude A. Okolie   +3 more
openaire   +1 more source

Groups and the Entropy Floor- XMM-Newton Observations of Two Groups

, 2002
Using XMM-Newton spatially resolved X-ray imaging spectroscopy we obtain the temperature, density, entropy, gas mass, and total mass profiles for two groups of galaxies out to ~0.3 Rvir (Rvir, the virial radius).
Figueroa-Feliciano, E., Loewenstein, M., Mushotzky, R., Snowden, S. L.   +3 more
core  

The Giant Flare of 1998 August 27 from SGR 1900+14: II. Radiative Mechanism and Physical Constraints on the Source

, 2001
(ABBREVIATED) The extraordinary 1998 August 27 giant flare places strong constraints on the physical properties of its source, SGR 1900+14. We make detailed comparisons of the published data with the magnetar model.
Barat C., Barat C., C. Thompson, Hulleman F., Lynden-Bell D., Mazets E. P., Mazets E. P., Paczynski B., R. C. Duncan, Thompson C.   +9 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Perlakuan Panas Mendidih Pada Pembuatan Milk-tea Dalam Kemasan (Kajian Pada Industri Skala Kecil) [PDF]

, 2016
Heating until boiling temperature has been a food safety standard for many Indonesian. The purpose of this study was to evaluate the effect of several heat treatment profiles towards the thermal death time value, pH, and microbiological aspect of bottled
M. Abduh, Setya Budi, Pratama, Y. (Yoga)
core  

Infrared and THz studies of polar phonons and improper magnetodielectric effect in multiferroic BFO3 ceramics

, 2006
BFO3 ceramics were investigated by means of infrared reflectivity and time domain THz transmission spectroscopy at temperatures 20 - 950 K, and the magnetodielectric effect was studied at 10 - 300 K, with the magnetic field up to 9 T.
D. Nuzhnyy, D. Y. Smith, F. Gervais, J. Kreisel, J. Petzelt, J. Prokleška, J. Šebek, M. Savinov, N. N. Krainik, P. Nalbach, R. Haumont, S. Kamba, Yu. E. Roginskaya, Yu. F. Popov   +13 more
core   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source