Results 91 to 100 of about 7,905,165 (291)

Third order perturbations of a zero-pressure cosmological medium: Pure general relativistic nonlinear effects

open access: yes, 2004
We consider a general relativistic zero-pressure irrotational cosmological medium perturbed to the third order. We assume a flat Friedmann background but include the cosmological constant.
A. A. Friedmann   +16 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Massive spin-2 particles via embedment of the Fierz-Pauli equations of motion

open access: yes, 2014
Here we obtain alternative descriptions of massive spin-2 particles by an embedding procedure of the Fierz-Pauli equations of motion. All models are free of ghosts at quadratic level although most of them are of higher order in derivatives.
Dalmazi, D.   +2 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Chiral perturbation theory at O(a^2) for lattice QCD

open access: yes, 2003
We construct the chiral effective Lagrangian for two lattice theories: one with Wilson fermions and the other with Wilson sea fermions and Ginsparg-Wilson valence fermions.
A. Morel   +38 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Study of soliton solutions of higher-order nonlinear Schrödinger dynamical model with derivative non-Kerr nonlinear terms and modulation instability analysis

open access: yesResults in Physics, 2019
In this work, soliton solutions of higher order non-linear Schrödinger equation (NLSE) with derivative non-Kerr non-linear terms are constructed by employing two analytical techniques, namely, exp(-Φ(ζ))-expansion and improved simple equation methods ...
Muhammad Arshad   +2 more
doaj   +1 more source

A Case Study on Logical Relations using Contextual Types

open access: yes, 2015
Proofs by logical relations play a key role to establish rich properties such as normalization or contextual equivalence. They are also challenging to mechanize.
Cave, Andrew, Pientka, Brigitte
core   +2 more sources

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