Results 101 to 110 of about 7,905,165 (291)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

HIGHER-ORDER CURVATURE TERMS IN BORN–INFELD TYPE BRANE THEORIES [PDF]

International Journal of Modern Physics D, 2011
The field equations associated to Born–Infeld type brane theories are studied by using auxiliary variables. This approach hinges on the fact, that the expressions defining the physical and geometrical quantities describing the worldvolume are varied independently.
openaire   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Perturbative quantization of two-dimensional space-time noncommutative QED

, 2009
Using the method of perturbative quantization in the first order approximation, we quantize a non-local QED-like theory including fermions and bosons whose interactions are described by terms containing higher order space-time derivatives. As an example,
D. Bahns, M. Ghasemkhani, M. Ostrogradski, N. Sadooghi, N. D. Birrell   +4 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Generalized XY Models with Arbitrary Number of Phase Transitions

Entropy
We propose spin models that can display an arbitrary number of phase transitions. The models are based on the standard XY model, which is generalized by including higher-order nematic terms with exponentially increasing order and linearly increasing ...
Milan Žukovič
doaj   +1 more source

Thermodynamics of Electrolytes.: V. Effects of Higher-Order Electrostatic Terms [PDF]

Journal of Solution Chemistry, 1975
The contribution of higher-order electrostatic terms (beyond the Debye-Huckel approximation) to the thermodynamic properties of mixed and pure electrolytes is investigated. It is found that these effects are important for cases of unsymmetrical mixing, especially when one ion has a charge of three units or more.
openaire   +2 more sources

Collider Production of TeV Scale Black Holes and Higher-Curvature Gravity

, 2005
We examine how the production of TeV scale black holes at colliders is influenced by the presence of Lovelock higher-curvature terms in the action of models with large extra dimensions.
, C. Lanczos, C.C. Briggs, C.M. Harris ., J. Tanaka, M. Bojowald, See M. Cavaglia, T. Clunan, T.G. Rizzo, Thomas G Rizzo, V.S. Rychkov   +10 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source