Results 121 to 130 of about 1,855,215 (295)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Higher-order reductions of the Mikhalev system [PDF]

We consider the 3D Mikhalev system, ut = wx, uy = wt − uwx + wux, which has first appeared in the context of KdV-type hierarchies. Under the reduction w = f(u), one obtains a pair of commuting first-order equations, ut = f′ux, uy = (f′2 − uf′ + f)ux ...
Vladimir Novikov (1259079), Ilia Roustemoglou (9305726), Evgeny Ferapontov (1259199)   +2 more
core   +2 more sources

Probabilistic Block Term Decomposition for the Modeling of Higher Order Arrays

Computing in Science & Engineering
Tensors are ubiquitous in science and engineering and tensor factorization approaches have become important tools for the characterization of higher order structure. Factorizations includes the outer-product rank Canonical Polyadic Decomposition (CPD) as well as the multi-linear rank Tucker decomposition in which the Block-Term Decomposition (BTD) is a
Jesper Løve Hinrich, Morten Mørup
openaire   +3 more sources

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Existence of solutions to nonlinear p-Laplacian fractional differential equations with higher-order derivative terms

Electronic Journal of Differential Equations, 2018
In this article, we discuss the existence of positive solution to a nonlinear p-Laplacian fractional differential equation whose nonlinearity contains a higher-order derivative $$\displaylines{ D_{0^+}^{\beta}\phi_p\big(D_{0^+}^{\alpha}u(t)\big) +f ...
You-Hui Su, Yongzhen Yun, Dongdong Wang, Weimin Hu   +3 more
doaj  

Higher order terms in an improved heteroticM-theory

Journal of High Energy Physics, 2008
8 pages ...
openaire   +3 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Retrieval of soliton solutions for 4th-order (2+1)-dimensional Schrödinger equation with higher-order odd and even terms by modified Sardar sub-equation method

Ain Shams Engineering Journal
This study examines the analytic wave solutions of a fourth-order (2+1)-dimensional nonlinear Schrödinger equation with higher-order odd and even terms using the modified Sardar sub-equation method.
Noha M. Kamel, Hamdy M. Ahmed, Wafaa B. Rabie   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Erratum to: Bouncing cosmology in modified gravity with higher-order curvature terms

Journal of High Energy Physics, 2023
J. K. Singh, Harshna Balhara, Kazuharu Bamba, J. Jena   +3 more
doaj   +1 more source