Results 51 to 60 of about 1,751,206 (262)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Multi-parameter crack tip stress state description for estimation of fracture process zone extent in silicate composite WST specimens [PDF]

Fracture and Structural Integrity, 2013
For wedge splitting test specimens, the stress and displacement fields both in the vicinity and also in larger distance from the crack tip are investigated by means of numerical methods. Several variants of boundary conditions were modeled.
Václav Veselý, Jakub Sobek, Lucie Šestáková, Petr Frantík, Stanislav Seitl   +4 more
doaj   +1 more source

Effects of Higher Order Retarded Gravity

Universe, 2021
In a recent paper, we have a shown that the flattening of galactic rotation curves can be explained by retardation. However, this will rely on a temporal change of galactic mass.
Asher Yahalom
doaj   +1 more source

Partial Dynamical Symmetry in Quantum Hamiltonians with Higher-Order Terms [PDF]

Physical Review Letters, 2009
A generic procedure is proposed to construct many-body quantum Hamiltonians with partial dynamical symmetry. It is based on a tensor decomposition of the Hamiltonian and allows the construction of a hierarchy of interactions that have selected classes of solvable states.
Garcia-Ramos, J. E., Leviatan, A., van Isacker, P.   +2 more
openaire   +5 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Pengembangan Buku Ajar Sejarah Fisika Berbasis Higher Order Thingking Skill (HOTS)

JPFT (Jurnal Pendidikan Fisika dan Teknologi), 2021
This study aims to develop and produce a physics history textbook based on higher order thinking skills (HOTS). This research was a development research which consists of four stages, namely: the determination stage, design, development, and ...
I Wayan Gunada, Syahrial Ayub, Aris Doyan, Ni Nyoman Sri Putu Verawati, Hikmawati Hikmawati   +4 more
doaj   +1 more source

Higher-order term indexing using substitution trees [PDF]

ACM Transactions on Computational Logic, 2009
We present a higher-order term indexing strategy based on substitution trees for simply typed lambda-terms. There are mainly two problems in adapting first-order indexing techniques. First, many operations used in building an efficient term index and retrieving a set of candidate terms from a large collection are undecidable in general for higher-order
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A Comprehensive Study on the Zeros of the Two-Parameter Mittag-Leffler Function [PDF]

Sahand Communications in Mathematical Analysis
The Mittag-Leffler function appears as an analytical solution of some fractional differential equations. The behavior of the zeros of the Mittag-Leffler function, especially their asymptotic distribution, plays a fundamental role in the study of ...
Farnoosh Abooali, Aliasghar Jodayree Akbarfam   +1 more
doaj   +1 more source

Nested Term Graphs (Work In Progress) [PDF]

Electronic Proceedings in Theoretical Computer Science, 2015
We report on work in progress on 'nested term graphs' for formalizing higher-order terms (e.g. finite or infinite lambda-terms), including those expressing recursion (e.g. terms in the lambda-calculus with letrec).
Clemens Grabmayer, Vincent van Oostrom
doaj   +1 more source