Results 91 to 100 of about 297,937 (262)

Bayesian Analysis of Continuous Time Models of the Australian Short Rate [PDF]

open access: yes
This paper provides an empirical analysis of a range of alternative single-factor continuous time models for the Australian short-term interest rate. The models are indexed by the level effect parameter for the volatility in the short rate process.
Andrew D. Sanford, Gael Martin
core  

Model Volatilitas ARCH(1) dengan Returns Error Berdistribusi non-central Student-t Studi Kasus: Kurs Beli JPY dan EUR terhadap IDR [PDF]

open access: yes, 2015
Studi ini mengaplikasikan model volatilitas Autoregressive Conditional Heteroscedasticity (ARCH) lag 1 untuk returns kurs beli Japanese Yen (JPY) dan Euro (EUR) terhadap Indonesian Rupiah (IDR) dari Januari 2009 sampai Desember 2014.
Nugroho, Didit B.   +2 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Statistical Inferences of Type-II Progressively Hybrid Censored Fuzzy Data with Rayleigh Distribution

open access: yesAustrian Journal of Statistics, 2018
This article presents the procedures for the estimation of the parameter of Rayleigh distribution based on Type-II progressive hybrid censored fuzzy lifetime data.
Ankita Chaturvedi   +2 more
doaj   +1 more source

Accelerating Metropolis-Hastings algorithms: Delayed acceptance with prefetching [PDF]

open access: yes, 2014
MCMC algorithms such as Metropolis-Hastings algorithms are slowed down by the computation of complex target distributions as exemplified by huge datasets. We offer in this paper an approach to reduce the computational costs of such algorithms by a simple
Banterle, Marco   +2 more
core   +1 more source

Bayesian nonparametric models for peak identification in MALDI-TOF mass spectroscopy

open access: yes, 2011
We present a novel nonparametric Bayesian approach based on L\'{e}vy Adaptive Regression Kernels (LARK) to model spectral data arising from MALDI-TOF (Matrix Assisted Laser Desorption Ionization Time-of-Flight) mass spectrometry.
Clyde, Merlise A.   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Exploiting network topology for large-scale inference of nonlinear reaction models

open access: yes, 2019
The development of chemical reaction models aids understanding and prediction in areas ranging from biology to electrochemistry and combustion. A systematic approach to building reaction network models uses observational data not only to estimate unknown
Galagali, Nikhil, Marzouk, Youssef M.
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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