Results 11 to 20 of about 21,476 (202)

Ribcage Morphology in Native South American Populations From Different Altitudes: Insights From a Global Comparative Framework. [PDF]

Am J Hum Biol
ABSTRACT Objectives Altitude shapes human morphology as highland populations must cope with cold and hypoxic environments. Although Andean highlanders have been proposed to exhibit larger and deeper ribcages, this idea is mainly based on research using disarticulated skeletal elements or non‐South American controls. The objective of this research is to
López-Rey JM, D'Angelo Del Campo MD, Bettera Marcat G, Arrieta M, Fabra M, Salega S, Mercolli P, Seldes V, García-Martínez D, Bastir M.   +9 more
europepmc   +2 more sources

Human adaptation to high-altitude: A contemporary comparison of the oxygen cascade in Andean, Tibetan and Ethiopian highlanders. [PDF]

Exp Physiol
Abstract Human populations native to high altitude have evolved distinct physiological adaptations to chronic hypoxia. This adaptation is evident in the O2 transport cascade. In this review, with brief inclusion of the related genetic adaptations, we compare the O2 cascade across three well‐characterized high‐altitude populations: Andeans (Aymara and ...
Getu AA, Ilardo M, Tremblay JC, Carr JMJR, Faoro V, Ainslie PN.   +5 more
europepmc   +2 more sources

Beyond Hemoglobin Concentration: How Intravascular Volume Measurements Can Advance Our Understanding of High-Altitude Adaptation. [PDF]

Am J Hum Biol
ABSTRACT Hemoglobin concentration is often interpreted as a marker for total hemoglobin mass in studies investigating high‐altitude adaptation. However, hemoglobin concentration is determined by both plasma volume and total hemoglobin mass. Therefore, using hemoglobin concentration as a marker for hemoglobin mass can obscure variation in total ...
Tremblay JC, Siebenmann C, Stembridge M.
europepmc   +2 more sources

High Altitude-Induced Pulmonary Hypertension: Our Scientific Journey to Prove Cold Exposure Is Also an Important Cause. [PDF]

Pulm Circ
Pulmonary Circulation, Volume 15, Issue 4, October 2025.
Kosanovic D.
europepmc   +2 more sources

Lipid and lipoprotein particle profiles in patients with type 2 diabetes mellitus: A comparative study between highlanders and lowlanders. [PDF]

Lipids
Abstract The lipid profiles of highlanders and lowlanders differ. However, studies of the lipid profiles of patients with type 2 diabetes mellitus (T2DM) living at high altitudes are limited. This study aimed to compare lipid profiles and lipoprotein particles in individuals with T2DM permanently residing in the Tibetan Plateau and those residing in ...
Zhang C, Du R, Wang S, Ye Y, Sun X, Wu Y, Li M.   +6 more
europepmc   +2 more sources

Born high, born fast: Does highland birth confer a pulmonary advantage for sea level endurance? [PDF]

Exp Physiol
Abstract Less than 7% of the world's population live at an altitude above 1500 m. Yet, as many as 67% of medalists in the 2020 men's and women's Olympic marathon, and 100% of medalists in the 2020 men's and women's Olympic 5000 m track race may have been born or raised above this otherwise rare threshold.
Paris HL, Baranauskas MN, Constantini K, Shei RJ, Allen PE, Jadovitz JR, Wiggins CC, Storm CP.   +7 more
europepmc   +2 more sources

Potential pitfalls of using a correction to normative values for the assessment of acid–base compensation during early ascent to high altitude [PDF]

Exp Physiol
Experimental Physiology, Volume 111, Issue 3, Page 1543-1545, 1 March 2026.
Bushfield N, Day T.
europepmc   +2 more sources

Time course of cerebral oxygenation and cerebrovascular reactivity in Kyrgyz highlanders. A five-year prospective cohort study

Frontiers in Physiology, 2023
Introduction: This prospective cohort study assessed the effects of chronic hypoxaemia due to high-altitude residency on the cerebral tissue oxygenation (CTO) and cerebrovascular reactivity.Methods: Highlanders, born, raised, and currently living above 2,
Matthias C. Luyken, Matthias C. Luyken, Paula Appenzeller, Paula Appenzeller, Philipp M. Scheiwiller, Philipp M. Scheiwiller, Mona Lichtblau, Mona Lichtblau, Maamed Mademilov, Maamed Mademilov, Aybermet Muratbekova, Aybermet Muratbekova, Ulan Sheraliev, Ulan Sheraliev, Ainura Abdraeva, Ainura Abdraeva, Nuriddin Marazhapov, Nuriddin Marazhapov, Talant M. Sooronbaev, Talant M. Sooronbaev, Silvia Ulrich, Silvia Ulrich, Konrad E. Bloch, Konrad E. Bloch, Michael Furian, Michael Furian   +25 more
doaj   +1 more source

The blunted vascular endothelial growth factor-A (VEGF-A) response to high-altitude hypoxia and genetic variants in the promoter region of the VEGFA gene in Sherpa highlanders [PDF]

PeerJ, 2022
Background Sherpa highlanders demonstrate extraordinary tolerance to hypoxia at high altitudes, which may be achieved by mechanisms promoting microcirculatory blood flow and capillary density at high altitudes for restoring oxygen supply to tissues ...
Yunden Droma, Masayuki Hanaoka, Takumi Kinjo, Nobumitsu Kobayashi, Masanori Yasuo, Yoshiaki Kitaguchi, Masao Ota   +6 more
doaj   +2 more sources

Relationships Between Chemoreflex Responses, Sleep Quality, and Hematocrit in Andean Men and Women. [PDF]

, 2020
Andean highlanders are challenged by chronic hypoxia and many exhibit elevated hematocrit (Hct) and blunted ventilation compared to other high-altitude populations.
Anza-Ramirez, Cecilia, Corante, Noemi, DeYoung, Pamela N, Djokic, Matea A, Gaio, Eduardo, Gilbertson, Dillon, Heinrich, Erica C, Macarlupu, Jose L, Malhotra, Atul, Orr, Jeremy E, Powell, Frank L, Simonson, Tatum S, Villafuerte, Francisco C, Vizcardo-Galindo, Gustavo   +13 more
core   +1 more source