Results 11 to 20 of about 21,415 (202)

Beyond Hemoglobin Concentration: How Intravascular Volume Measurements Can Advance Our Understanding of High-Altitude Adaptation. [PDF]

Am J Hum Biol
ABSTRACT Hemoglobin concentration is often interpreted as a marker for total hemoglobin mass in studies investigating high‐altitude adaptation. However, hemoglobin concentration is determined by both plasma volume and total hemoglobin mass. Therefore, using hemoglobin concentration as a marker for hemoglobin mass can obscure variation in total ...
Tremblay JC, Siebenmann C, Stembridge M.
europepmc   +2 more sources

High Altitude-Induced Pulmonary Hypertension: Our Scientific Journey to Prove Cold Exposure Is Also an Important Cause. [PDF]

Pulm Circ
Pulmonary Circulation, Volume 15, Issue 4, October 2025.
Kosanovic D.
europepmc   +2 more sources

Born high, born fast: Does highland birth confer a pulmonary advantage for sea level endurance? [PDF]

Exp Physiol
Abstract Less than 7% of the world's population live at an altitude above 1500 m. Yet, as many as 67% of medalists in the 2020 men's and women's Olympic marathon, and 100% of medalists in the 2020 men's and women's Olympic 5000 m track race may have been born or raised above this otherwise rare threshold.
Paris HL, Baranauskas MN, Constantini K, Shei RJ, Allen PE, Jadovitz JR, Wiggins CC, Storm CP.   +7 more
europepmc   +2 more sources

Lipid and lipoprotein particle profiles in patients with type 2 diabetes mellitus: A comparative study between highlanders and lowlanders. [PDF]

Lipids
Abstract The lipid profiles of highlanders and lowlanders differ. However, studies of the lipid profiles of patients with type 2 diabetes mellitus (T2DM) living at high altitudes are limited. This study aimed to compare lipid profiles and lipoprotein particles in individuals with T2DM permanently residing in the Tibetan Plateau and those residing in ...
Zhang C, Du R, Wang S, Ye Y, Sun X, Wu Y, Li M.   +6 more
europepmc   +2 more sources

Addressing Anemia in High-Altitude Populations: Global Impact, Prevalence, Challenges, and Potential Solutions. [PDF]

Am J Hematol
Key challenges in diagnosing anemia in high‐altitude populations include variability in hemoglobin (Hb) concentration, associated pathological conditions, altitude‐induced plasma volume changes, and environmental factors such as contamination and nutrition.
Boulares A, Bragazzi NL, Gonzales GF, Robach P, Champigneulle B, Brugniaux JV, Stauffer E, Nader E, Doutreleau S, Connes P, Verges S, Pichon A.   +11 more
europepmc   +2 more sources

Spirometry in Central Asian Lowlanders and Highlanders, a Population Based Study

Frontiers in Medicine, 2020
Introduction: The purpose of the study was to establish spirometric reference values for a Central Asian population of highlanders and lowlanders.Methods: Spirometries from a population-based cross-sectional study performed in 2013 in rural areas of ...
Stefanie Ulrich, Michael Furian, Bermet Estebesova, Nurgul Toktogulova, Gulnara Beishekeeva, Silvia Ulrich, Peter G. J. Burney, Talant M. Sooronbaev, Konrad E. Bloch   +8 more
doaj   +1 more source

«Those fleeing from the cruelty of the owners should be taken under the protection of…»: prisoners and fugitives on the Kuban border in the 20s of the xix century (according to the State archive of Krasnodar region)

Гуманитарные и юридические исследования, 2022
The geopolitical realities that developed as a result of the victory of the Russian Empire in the war against Turkey in 1787 – 1791 carried new challenges for St. Petersburg related to the arrangement of the border along the Kuban River.
N. S. Tkalenko
doaj   +1 more source

Physiological Differences Underlying Divergent Hypoxia Responses and Altitude Adaptations in Humans, Rats and Mice. [PDF]

Compr Physiol
Despite many physiological similarities, mice, rats and humans respond remarkably differently to hypoxia. In line with their high‐altitude phylogeographic history, mice are physiologically well equipped to deal better with high‐altitude hypoxia than humans, while the low‐land origin of rats may be associated with a particularly high vulnerability to ...
Burtscher J, Mallet RT, Sah A, Gassmann M, Burtscher M, Iturriaga R.   +5 more
europepmc   +2 more sources

Relationships Between Chemoreflex Responses, Sleep Quality, and Hematocrit in Andean Men and Women. [PDF]

, 2020
Andean highlanders are challenged by chronic hypoxia and many exhibit elevated hematocrit (Hct) and blunted ventilation compared to other high-altitude populations.
Anza-Ramirez, Cecilia, Corante, Noemi, DeYoung, Pamela N, Djokic, Matea A, Gaio, Eduardo, Gilbertson, Dillon, Heinrich, Erica C, Macarlupu, Jose L, Malhotra, Atul, Orr, Jeremy E, Powell, Frank L, Simonson, Tatum S, Villafuerte, Francisco C, Vizcardo-Galindo, Gustavo   +13 more
core   +1 more source

The blunted vascular endothelial growth factor-A (VEGF-A) response to high-altitude hypoxia and genetic variants in the promoter region of the VEGFA gene in Sherpa highlanders [PDF]

PeerJ, 2022
Background Sherpa highlanders demonstrate extraordinary tolerance to hypoxia at high altitudes, which may be achieved by mechanisms promoting microcirculatory blood flow and capillary density at high altitudes for restoring oxygen supply to tissues ...
Yunden Droma, Masayuki Hanaoka, Takumi Kinjo, Nobumitsu Kobayashi, Masanori Yasuo, Yoshiaki Kitaguchi, Masao Ota   +6 more
doaj   +2 more sources