Results 191 to 200 of about 96,616 (241)

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

The Anatomical Record, EarlyView.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille, Kyla Beguesse, Ewan Wolff, Clemens Zinner, Patrick Asbach, François Clarac, Florian Witzmann   +6 more
wiley   +1 more source

A systematic review of consensus recommendations and guidelines on the management and care of women with multiple sclerosis through pre-pregnancy, pregnancy, and postpartum periods. [PDF]

BMC Neurol
Ghezelhesari EM, Tehrani MV, Nahayati M, Ebrahimipour H, Heydari A, Khadivzadeh T.   +5 more
europepmc   +1 more source

Pathophysiological Mechanisms of Emaciation Syndrome in Plectropomus leopardus: Insights From Histology and Transcriptomics

Animal Research and One Health, EarlyView.
Integrated phenotypic, histological, transcriptomic, and validation analyses reveal that emaciation syndrome in Plectropomus leopardus is associated with intestinal structural damage, hepatic metabolic remodeling, and muscle protein degradation, highlighting coordinated multi‐tissue alterations underlying disease progression.
Zhihao Zhang, Bo Wang, Mengya Wang, Haizhan Tang, Mingjian Liu, Da Zheng, Zhongyi Zhai, Jiahang Li, Jinyang Xie, Chaofan Jin, Jingjie Hu, Zhenmin Bao   +11 more
wiley   +1 more source

Systematic Review of Monoclonal Antibody Therapies in Relapsing Multiple Sclerosis: Comparator-Stratified Analysis of Relapse and Disability Outcomes. [PDF]

Med Sci (Basel)
Ciubotaru A, Grosu C, Maștaleru A, Constantinescu V, Alexa D, Covali R, Riscanu L, Bilcu RV, Cucu LE, Gațcan C, Socolov-Mihaita SA, Lăcătușu D, Crivoi F, Vamanu A, Patrascu A, Ignat EB.   +15 more
europepmc   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

The Potential Role of Synovial T Cell Infiltration Following Knee Joint Injury in Symptoms and Progression to Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Identification of osteoarthritis (OA)–specific synovial inflammatory pathways and their temporal relevance is critical for therapeutic targeting. We compared mononuclear inflammatory/immune cell responses following joint injury that does or does not lead to OA to define bona fide OA‐associated cellular events.
Babak Moradi, Miriam T. Jackson, Cindy C. Shu, Susan M. Smith, Margaret M. Smith, Sanaa Zaki, Hadrian Platzer, Nils Rosshirt, David Giangreco, Carla R. Scanzello, Christopher B. Little   +10 more
wiley   +1 more source

Early Prognostic Factors in Multiple Sclerosis: Clinical and Therapeutic Implications. [PDF]

Medicina (Kaunas)
Maciejowska-Szydło K, Puz P.
europepmc   +1 more source

A National Danish Effectiveness Study of Ocrelizumab Versus Natalizumab in Multiple Sclerosis. [PDF]

Eur J Neurol
Maersk-Moller C, Pontieri L, Stilund MLM, Christensen JR, Storr LK, Hansen V, Schäfer J, Weglewski A, Romani KQ, Jensen HB, Illes Z, Papp V, Sejbaek T, Poulsen MB, Kant M, Torring CW, Sellebjerg F, Magyari M, DMSG Group.   +18 more
europepmc   +1 more source

HerMeS: a registry-based evaluation of the HERCULES criteria for identifying nonrelapsing SPMS. [PDF]

J Neurol
Guerra T, Lucisano G, Rocca MA, Cocco E, Patti F, De Luca G, Portaccio E, Foschi M, Ferraro D, Pozzilli C, Romano S, Annovazzi P, Brescia Morra V, Tortorella C, Fantozzi R, Perini P, Coniglio MG, Salemi G, Inglese M, Maniscalco GT, Torri Clerici VLAM, Lugaresi A, Lus G, Colombo E, Granella F, Cavalla P, Di Sapio A, Conte A, Cerqua R, Totaro R, Caputo F, Paolicelli D, Farina A, Mondino MM, Todaro DS, Olivieri N, Amato MP, Filippi M, Trojano M, Iaffaldano P, Italian Multiple Sclerosis and Related Disorders Register (RISM).   +40 more
europepmc   +1 more source