Results 201 to 210 of about 96,616 (241)

Importance of physiotherapy and occupational therapy according to people with multiple sclerosis-results from an online survey. [PDF]

Front Rehabil Sci
Beckerman H, Coppers JPMA, Eijssen ICJM.
europepmc   +1 more source

Nutrients and bioactive compounds as modifiers of neurodegenerative trajectories: molecular mechanisms, translational barriers, and precision nutrition. [PDF]

Front Nutr
Singh G, Singh G, Shreya, Kumari A, Aran KR.   +4 more
europepmc   +1 more source

PRIMUS: a precision medicine platform reusing clinical trials and registry data to support treatment selection in multiple sclerosis. [PDF]

JAMIA Open
Demuth S, Faddeenkov I, Paris J, Rousseau O, Baciotti B, Payet M, Casey R, Vukusic S, Doyle S, Jarre G, Vince N, Limou S, De Sèze J, Kerbrat A, Laplaud D, Edan G, Gourraud PA, PRIMUS Consortium.   +17 more
europepmc   +1 more source

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Highly active multiple sclerosis: An update

Multiple Sclerosis and Related Disorders, 2019
Multiple sclerosis (MS) is the most prevalent chronic inflammatory disease of the central nervous system (CNS), affecting more than 2 million people worldwide. It is characterized by brain and spinal cord involvement. There are the relapsing remitting MS (RRMS), primary progressive MS (PPMS), and secondary progressive MS (SPMS) phenotypes.
Cindy Andrea Diaz Becerra, Luis Alfonso Zarco Montero   +1 more
exaly   +3 more sources

Highly Active Multiple Sclerosis

2021
A 16-year-old girl was evaluated for symptoms of thoracic myelitis with sensory loss below T12, gait difficulty, constipation, and incomplete bladder emptying. On evaluation, she had a flat affect, normal cranial nerve function, and normal motor examination findings. Deep tendon reflexes were symmetric, and plantar responses were flexor.
Roman Kassa, W. Oliver Tobin
exaly   +2 more sources

Different neuroinflammatory gene expression profiles in highly active and benign multiple sclerosis

Journal of Neuroimmunology, 2021
In this study, we aimed to explore the expression of genes associated with neuroinflammation in patients with benign and highly active multiple sclerosis (MS) and healthy controls, to define gene signatures associated with MS as well as disease activity and progression. We identified differences in the expression of 89 genes in benign and highly active
Vladimir Sukhorukov, Mariya Zakharova
exaly   +3 more sources

Efficacy of fingolimod in patients with highly active relapsing–remitting multiple sclerosis

Current Medical Research and Opinion, 2015
There is a need to identify effective switch therapies for patients with relapsing-remitting multiple sclerosis (RRMS) who experience high disease activity despite receiving disease-modifying therapy (DMT). The objective of this study was to assess the efficacy of fingolimod versus placebo in patients with RRMS who had experienced high disease activity
Derfuss, T., Bergvall, N. K., Sfikas, N., Tomic, D. L.   +3 more
exaly   +5 more sources

Differential white and gray matter damage in highly active multiple sclerosis: A prospective cohort study

Journal of Clinical Neuroscience, 2020
We analyze the differential brain volume changes in highly active multiple sclerosis (HAMS) vs. non-HAMS patients during the disease onset.HAMS was defined as: a) patients with 1 relapse in the previous year and at least 1 T1 gadolinium-enhancing lesion or 9 or more T2 lesions while on therapy with other disease modifying treatment (DMD); or b ...
Agustin Pappolla, Edgardo Cristiano, FRANCISCO Sanchez   +2 more
exaly   +3 more sources