Results 71 to 80 of about 328,763 (284)

Run-Time Risk Mitigation in Automated Vehicles: A Model for Studying Preparatory Steps [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2017
We assume that autonomous or highly automated driving (AD) will be accompanied by tough assurance obligations exceeding the requirements of even recent revisions of ISO 26262 or SOTIF.
Mario Gleirscher
doaj   +1 more source

Too sick to drive : how motion sickness severity impacts human performance [PDF]

open access: yes, 2018
There are multiple concerns surrounding the development and rollout of self-driving cars. One issue has largely gone unnoticed - the adverse effects of motion sickness as induced by self-driving cars.
Birrell, Stewart A.   +3 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Generating Comfortable, Safe and Comprehensible Trajectories for Automated Vehicles in Mixed Traffic

open access: yes, 2018
While motion planning approaches for automated driving often focus on safety and mathematical optimality with respect to technical parameters, they barely consider convenience, perceived safety for the passenger and comprehensibility for other traffic ...
Lauer, Martin   +2 more
core   +1 more source

Highly automated driving with a decoupled steering wheel [PDF]

open access: yesProceedings of the Human Factors and Ergonomics Society Annual Meeting, 2014
Future cars will almost certainly provide an increasing level of automation. Under certain conditions, they will allow the driver to withdraw from the control loop and deal with non-driving related tasks. To provide a convenient and safe user interface for this case, it can be advantageous to have the steering wheel de-coupled from the steering link ...
Philipp Kerschbaum   +2 more
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

TrafficNet: An Open Naturalistic Driving Scenario Library

open access: yes, 2017
The enormous efforts spent on collecting naturalistic driving data in the recent years has resulted in an expansion of publicly available traffic datasets, which has the potential to assist the development of the self-driving vehicles.
Guo, Yaohui   +2 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Takeover Requests in Highly Automated Truck Driving: How Do the Amount and Type of Additional Information Influence the Driver–Automation Interaction?

open access: yesMultimodal Technologies and Interaction, 2018
Vehicle automation is linked to various benefits, such as increase in fuel and transport efficiency as well as increase in driving comfort. However, automation also comes with a variety of possible downsides, e.g., loss of situational awareness, loss of ...
Natalie T. Richardson   +2 more
doaj   +1 more source

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