Results 241 to 250 of about 852,985 (355)

Highly pathogenic avian influenza A (H5N1) virus

Canadian Medical Association Journal
Kozak, Robert, Bogoch, Isaac I., Mubareka, Samira   +2 more
openaire   +2 more sources

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Genomic and evolutionary characterization of newly emerged highly pathogenic avian influenza H5N1 clade (2023-2025). [PDF]

Vet World
Shosha EAE, Mohamd MK, Shehata MAE, Mohamed MH, Eldaghayes IM, Abdelhafez MS.   +5 more
europepmc   +1 more source

Inoculation with highly pathogenic avian influenza H5N1 genotype D1.1 in naïve dairy cows and dairy cows previously exposed to genotype B3.13 [PDF]

Kaitlyn Sarlo Davila, Meghan Wymore Brand, E. J. Putz, Paola M. Boggiatto, Hannah Seger, A. L. Baker, Tavis K. Anderson, Carl R. Hutter, Alexandra Buckley, Allison Vander Plaats, Rachel Friedrich, Patrick Gordon, Bailey Arruda, Carine K. Souza, B.D. Davidson, M. J. Palmer   +15 more
openalex   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

The prevalence of highly-pathogenic viruses in European wildcat and Eurasian Lynx in Poland. [PDF]

Vet Res Commun
Didkowska A, Matusik K, Klich D, Schmidt K, Kwiecień E, Wódz K, Kwieciński P, Wójcik W, Anusz K, Kołodziej-Sobocińska M.   +9 more
europepmc   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Converging threats: The intersection of seasonal influenza surges and zoonotic highly pathogenic avian influenza. [PDF]

Glob Health Med
Yang W, Xiong H, Zhao R, Yang Y, Lu H.
europepmc   +1 more source

Workshop – Assessing risks of introduction of highly pathogenic avian influenza virus via wild birds [PDF]

, 2016
European Food Safety Authority (EFSA)
openalex   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source