Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Dove, Brian K. +35 more
core +1 more source
This study highlights that most consumers recognize that meat can transmit zoonotic diseases. However, substantial gaps persist in specific knowledge and in the consistent adoption of safe handling practices. By combining community education, improved market hygiene and One Health initiatives, policy‐makers can substantially reduce exposure to zoonotic
Madi Savadogo +6 more
wiley +1 more source
Species-Specific Contribution of the Four C-Terminal Amino Acids of Influenza A Virus NS1 Protein to Virulence [PDF]
Large-scale sequence analyses of influenza viruses revealed that nonstructural 1 (NS1) proteins from avian influenza viruses have a conserved C-terminal ESEV amino acid motif, while NS1 proteins from typical human influenza viruses have a C-terminal RSKV
Loupias, Josiane +12 more
core +1 more source
Spatial projections revealed high‐risk areas for YF transmission, highlighting priority zones for targeted vaccination efforts in GLTs. By integrating disease ecology into conservation planning, this study offers a scalable framework for spatially informed interventions aimed at mitigating disease‐driven declines in threatened species.
Maxime Pierron +5 more
wiley +1 more source
Application of chicken microarrays for gene expression analysis in other avian species [PDF]
With the threat of emerging infectious diseases such as avian influenza, whose natural hosts are thought to be a variety of wild water birds including duck, we are armed with very few genomic resources to investigate large scale immunological gene ...
Moore, Robert J +3 more
core +1 more source
Experimental infection of dogs with highly pathogenic avian influenza virus (H5N8)
During the highly pathogenic avian influenza (HPAI) H5N8 virus outbreak in Korea, a dog in layer farm contaminated by H5N8 was reported seropositive for HPAI H5N8. To investigate the possibility of adaptation and transmission of HPAI H5N8 to dogs, we experimentally inoculated dogs with H5N8.
Yuk, Seong-Su +6 more
openaire +2 more sources
We compared the characteristics of cases of highly pathogenic avian influenza (HPAI) and low pathogenic avian influenza (LPAI) A(H7N9) virus infections in China. HPAI A(H7N9) case-patients were more likely to have had exposure to sick and dead poultry in
Lei Zhou +20 more
doaj +1 more source
Assessing Risk Thresholds in Controlled Human Infection Models (CHIM)
ABSTRACT Controlled Human Infection Models (CHIMs) are a type of clinical trial involving deliberately exposing human volunteers to an infectious agent. Compared to studies of natural infection, CHIMs offers distinctive benefits, from the ability to study presymptomatic infection to a direct assessment of the efficacy of vaccines and therapeutics in a ...
Alexa Nord‐Bronzyk +4 more
wiley +1 more source
Phylogenetic and molecular characteristics of Eurasian H9 avian influenza viruses and their detection by two different H9-specific RealTime reverse transcriptase polymerase chain reaction tests [PDF]
Avian influenza viruses (AIVs) of the H9 haemagglutinin subtype are endemic in many Asian and Middle-East countries, causing mortality and morbidity in poultry.
Krill, D. +9 more
core +1 more source
Characteristics of influenza H13N8 subtype virus firstly isolated from Qinghai Lake Region, China
Background Since the highly pathogenic H5N1 influenza caused thousands of deaths of wild bird in this area in 2005, Qinghai Lake in China has become a hot spot for study of the influence of avian influenza to migratory wild birds.
Jie Dong +8 more
doaj +1 more source

