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Influence of Reduced Field Strength on Product Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2021
Classical ion mobility spectrometers (IMS) operated at ambient pressure, often use atmospheric pressure chemical ionization (APCI) sources to ionize organic compounds. In APCI, reactant ions ionize neutral analyte molecules via gas-phase ion–molecule reactions. The positively charged reactant ions in purified, dry air are H3O+, NO+, and O2+•.
Ansgar T Kirk   +2 more
exaly   +5 more sources

Influence of Sample Gas Humidity on Product Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2022
High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) chemically ionize gaseous samples via reactant ions and separate the generated ions by their motion in a neutral gas under the influence of an electric field. Operation at reduced pressures of 10–40 mbar allows for reaching high reduced electric field strengths (E/N) of up to 120 Td.
Ansgar T Kirk   +2 more
exaly   +5 more sources

Analyzing Positive Reactant Ions in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) by HiKE-IMS–MS

Journal of the American Society for Mass Spectrometry, 2020
In contrast to classical ion mobility spectrometers (IMS) operating at ambient pressure, the high kinetic energy ion mobility spectrometer (HiKE-IMS) is operated at reduced pressures between 10-40 mbar. In HiKE-IMS, ions are generated in a reaction region before they are separated in a drift region.
Ansgar T Kirk   +2 more
exaly   +3 more sources

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