Results 171 to 180 of about 61,808 (305)

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

Developmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard, Lauren Clarissa Tang, Beatrix Ueberheide, Lisa A. Taneyhill   +3 more
wiley   +1 more source

Influence of Longitudinal Center of Mass Position on Load Distribution in High-Speed Quadrupedal Locomotion. [PDF]

Biomimetics (Basel)
Lan K, Jiang L, Tao Y, Fu C, Jin Y, Wang H.   +5 more
europepmc   +1 more source

Three‐dimensional observation of the muscle–tendon integration process in mouse embryos

Developmental Dynamics, EarlyView.
Abstract Background Muscle–tendon integration is a crucial step in the morphogenesis of the vertebrate locomotion system. As the limb muscle and tendon progenitor cells derive from distinct embryonic origin, their integration requires precise mutual positioning.
Ramu Sagasaki, Anzu Taniguchi, Shunsuke Oka, Mizuki Mishima, Yuki Yamasaki, Yutaro Kawa, Saundra Schlesinger, Ryo Fujita, Chisa Shukunami, Hiroshi Asahara, Masafumi Inui   +10 more
wiley   +1 more source

3D bioprinted human vascular organoid sheets promote functional ischemic repair and exhibit adaptive in vivo remodeling. [PDF]

BMC Med
Fu X, Yan L, Chen Z, Dou B, Zhou D, Zhou X, Qu K, Gao C, Wang P, Zhang F, Zou Z, Wang T, Li G, Ouyang L, Na J.   +14 more
europepmc   +1 more source

A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)

Developmental Dynamics, EarlyView.
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble, Samantha L. Payne, Matthew K. Vickaryous   +2 more
wiley   +1 more source

A compact, wireless fluorimeter system for continuous, real-time monitoring of tissue perfusion via in vivo fluorescence signals. [PDF]

Sci Adv
Park TW, Zhang H, Park C, Goldstein SD, Wade L, Rytkin E, McLuckie AJ, Kulahci Y, Janarthanan R, Kim TY, Jo MS, Sazoglu B, Demir Z, Dirican O, Demir FE, Maeng WY, Yoo S, Saba P, Zhang K, Ahn HY, Kim JU, Lee J, Banks A, Oh S, Kwon K, Nugent A, Efimov IR, Gorantla VS, Pelech A, Huang Y, Rogers JA.   +30 more
europepmc   +1 more source

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor, E. N. Chow, M. Thomas, L. Johnson, A. Siefert, B. Wagner, J. B. Engiles, H. L. Reesink   +7 more
wiley   +1 more source

Neuronal Regulation and Locomotion in Rats Following Spinal Cord Injury: Reconciling Behavioral Scales With Neuroelectrophysiology. [PDF]

Neurosci Insights
All AH.
europepmc   +1 more source

Laser neoureterocystostomy to treat ectopic ureters

Equine Veterinary Journal, EarlyView.
Abstract Background Ureteral ectopia is an uncommon but clinically important congenital abnormality in horses. If left untreated, it can lead to persistent dermatitis, urinary tract infections, and failure to thrive. Surgical correction is necessary, but traditional approaches have produced mixed results with high morbidity.
Caitlin Smith, Eric J. Parente
wiley   +1 more source

A Novel Preclinical Rat Model of Acute Compartment Syndrome. [PDF]

J Orthop Res
Guan S, Lu X, Liu C, Zhang Y, Li Y, Zhao H, Zhang L.   +6 more
europepmc   +1 more source