An Investigation of the Role of Ridden Exercise, Including Application of the Ridden Horse Pain Ethogram, in Pre-Purchase Examinations of Sports Horses. [PDF]
Dyson S.
europepmc +1 more source
Abstract Background Force plates (FP) are considered the gold standard for quantitative equine gait evaluation but are limited to experimental use. An instrumented hoof boot (IHB) with pressure sensors and an inertial measurement unit would allow clinicians to objectively assess kinetic parameters and gait symmetry.
Jasmin Keller +3 more
wiley +1 more source
Immediate post-injury HMGB1 neutralization prevents synaptic dysfunction in burn and hindlimb unloaded rats. [PDF]
Sreenivasa Murthy SGS +7 more
europepmc +1 more source
Triggered Calcium Lightning Programs Cochlear Development
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma +13 more
wiley +1 more source
Distinctive Innervation Patterns of Thigh Extensor Muscles in Anura: A Morphogenetic Hypothesis of Nerve Re-Routing Within the Hindlimb Plexus in the Tetrapod Evolutionary Process. [PDF]
Anetai H +6 more
europepmc +1 more source
Osteoarthritis pain arises not only from joint damage but also from inflammation, abnormal bone changes, and excessive nerve activation inside the joint. In this study, we developed an injectable nanomedicine, LAC, that responds to the acidic environment of osteoarthritic joints to locally release two approved drugs, reducing inflammation, limiting ...
Junyan Liu +12 more
wiley +1 more source
Endovascular dual internal-external iliac balloon occlusion creates a reproducible porcine survival model of unilateral acute hindlimb ischemia. [PDF]
Tabesh A +8 more
europepmc +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Human Decellularized Adipose Tissue Hydrogels as a Delivery Platform to Enhance Human Endothelial Colony-Forming Cell Retention and Vascular Regeneration. [PDF]
Terek AE +5 more
europepmc +1 more source
Novel Injectable Supports Long‐Term Recurrent Laryngeal Nerve and Partial Peripheral Nerve Repair
Following recurrent laryngeal nerve transection in C57BL/6 mice, intramuscular Agrin, neuregulin‐1, and acetylcholine treatment of the thyroarytenoid muscle supported functional reinnervation and preservation of neuromuscular structure at 84 days.
Aditya Bhatt +10 more
wiley +1 more source

