Results 21 to 30 of about 49,698 (296)

Inhibiting myostatin signaling partially mitigates structural and functional adaptations to hindlimb suspension in mice

npj Microgravity, 2023
Novel treatments for muscle wasting are of significant value to patients with disease states that result in muscle weakness, injury recovery after immobilization and bed rest, and for astronauts participating in long-duration spaceflight.
Andrea M. Hanson, Mary H. Young, Brooke C. Harrison, Xiaolan Zhou, H. Q. Han, Louis S. Stodieck, Virginia L. Ferguson   +6 more
doaj   +1 more source

DNase I and Sivelestat Ameliorate Experimental Hindlimb Ischemia-Reperfusion Injury by Eliminating Neutrophil Extracellular Traps

Journal of Inflammation Research, 2023
Chun-Lian Wang,1 Yan Wang,2 Qi-Lan Jiang,3 Yang Zeng,4 Qing-Ping Yao,5 Xing Liu,6 Tao Li,7 Jun Jiang1 1Department of General Surgery (Thyroid Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, People’s Republic of China ...
Wang CL, Wang Y, Jiang QL, Zeng Y, Yao QP, Liu X, Li T, Jiang J   +7 more
doaj  

Cordymin alleviates osteoporosis induced by hindlimb unloading via regulating the gut - microelements -bone axis --for non-clinical studies

BMC Musculoskeletal Disorders, 2023
Introduction The purpose of this study was to evaluate the protective effects of cordymin on osteoporosis induced by hindlimb unloading(HLU) in rats and whether cordymin can prevent bone loss from HLU.
Wei Qi, Tiancheng Ma, Yufei Ji, Hong Jia, Qiang Sun, Dawei Zhang   +5 more
doaj   +1 more source

Pharmacological and Genetic Inhibition of PD-1 Demonstrate an Important Role of PD-1 in Ischemia-Induced Skeletal Muscle Inflammation, Oxidative Stress, and Angiogenesis

Frontiers in Immunology, 2021
Angiogenesis is an important process under both physiological and pathophysiological conditions. Here we investigated the role and the underlying mechanism of PD-1 in hindlimb ischemia-induced inflammation and angiogenesis in mice.
Xiaoguang Liu, Xinyu Weng, Xinyu Weng, Weihua Xiao, Xin Xu, Yingjie Chen, Yingjie Chen, Peijie Chen   +7 more
doaj   +1 more source

Radiographic Morphometric Measurements of the Donkey’s Distal Hind Limb

Animals
Morphometric measurements of the toe serve as a reference for the objective assessment of the presence of a pathological condition and as a guide for the correct trimming of the hooves.
Kyra Schaus, Juliana Wacker, Anabell Jandowsky, Kathrin Büttner, Michael Röcken, Claus Peter Bartmann   +5 more
doaj   +1 more source

Pitx1 determines characteristic hindlimb morphologies in cartilage micromass culture.

PLoS ONE, 2017
The shapes of homologous skeletal elements in the vertebrate forelimb and hindlimb are distinct, with each element exquisitely adapted to their divergent functions.
Natalie C Butterfield, Chen Qian, Malcolm P O Logan   +2 more
doaj   +1 more source

Functional analysis of a first hindlimb positioning enhancer via Gdf11 expression

Frontiers in Cell and Developmental Biology
During the early development of tetrapods, including humans, the embryonic body elongates caudally once the anterior-posterior axis is established.
Seiji Saito, Utsugi Kanazawa, Ayana Tatsumi, Atsuo Iida, Tatsuya Takemoto, Takayuki Suzuki   +5 more
doaj   +1 more source

Dynamic transcriptome and histomorphology analysis of developmental traits of hindlimb thigh muscle from Odorrana tormota and its adaptability to different life history stages

BMC Genomics, 2021
Background Systematic studies on the development and adaptation of hindlimb muscles in anura amphibians are rare. Here, we integrated analysis of transcriptome and histomorphological data for the hindlimb thigh muscle of Odorrana tormota (concave-eared ...
Yilin Shu, Jun He, Huijuan Zhang, Guangxuan Liu, Shikun Li, Shuaitao Deng, Hailong Wu   +6 more
doaj   +1 more source

Characterization of the arterial anatomy of the murine hindlimb: functional role in the design and understanding of ischemia models.

PLoS ONE, 2013
RationaleAppropriate ischemia models are required for successful studies of therapeutic angiogenesis. While collateral routes are known to be present within the innate vasculature, there are no reports describing the detailed vascular anatomy of the ...
Takashi Kochi, Yoshimichi Imai, Atsushi Takeda, Yukiko Watanabe, Shiro Mori, Masahiro Tachi, Tetsuya Kodama   +6 more
doaj   +1 more source

Decoding Bilateral Hindlimb Kinematics From Cat Spinal Signals Using Three-Dimensional Convolutional Neural Network

Frontiers in Neuroscience, 2022
To date, decoding limb kinematic information mostly relies on neural signals recorded from the peripheral nerve, dorsal root ganglia (DRG), ventral roots, spinal cord gray matter, and the sensorimotor cortex.
Yaser Fathi, Abbas Erfanian, Abbas Erfanian   +2 more
doaj   +1 more source