Results 31 to 40 of about 384,907 (264)

Clinical Outcomes and Return to Sport in Competitive Athletes Undergoing Iliopsoas Fractional Lengthening as a Part of Hip Arthroscopy - Minimum Two-Year Follow-Up

Orthopaedic Journal of Sports Medicine, 2017
Objectives: The iliopsoas is a hip flexor and stabilizer that may be associated with internal snapping. Although flexion and stability are important in competitive athletes, painful internal snapping may be debilitating and may necessitate arthroscopic ...
Itay Perets MD, David Edward Hartigan MD, John P. Walsh MA, Edwin Chaharbakhshi BS, Mary R. Close BS, Benjamin G. Domb MD   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Outcomes of 1038 Hip Arthroscopies

Orthopaedic Journal of Sports Medicine, 2015
Objectives: The purpose of this study was to evaluate clinical outcomes, pain, and patient satisfaction following all hip arthroscopies performed by a single surgeon at a high volume referral center with a mean 2-year follow-up. Methods: During the study
Parth Lodhia MD, Tim Martin MA, Chengcheng Gui BSE, Christine E. Stake MA, S Pavan Vemula MA, Carlos Suarez-Ahedo MD, Sivashankar Chandrasekaran MD, Benjamin G. Domb MD   +7 more
doaj   +1 more source

Do Not Take for Granted! The Art of Elevating the Capsule in Hip Arthroscopy: A Stepwise Approach

Arthroscopy Techniques, 2019
Different techniques have been described to close or plicate the capsule. To perform these procedures, however, the capsule must be preserved, a consideration unfortunately often overlooked.
David R. Maldonado, M.D., Jeffrey W. Chen, B.A., Ajay C. Lall, MD, M.S., Cynthia Kyin, B.A., Rafael Walker-Santiago, M.D., Philip J. Rosinsky, M.D., Jacob Shapira, M.D., Benjamin G. Domb, M.D.   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Effect of Preoperative Opioid Consumption on Outcomes After Hip Arthroscopy for Femoroacetabular Impingement and Labral Tears: A Minimum 2-Year Follow-up Study

Orthopaedic Journal of Sports Medicine
Background: There is a paucity of literature investigating the effect of preoperative opioid use on outcomes after hip arthroscopy. Purpose: To evaluate the short-term outcomes and the recovery curve of patients undergoing hip arthroscopy for ...
Roger Quesada-Jimenez MD, Dharma H. Patel BA, Ady H. Kahana-Rojkind MD, Meredith F. Cohen BA, Benjamin D. Kuhns MD, Benjamin G. Domb MD   +5 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Microfracture in Hip Arthroscopy. Keep It Simple!

Arthroscopy Techniques, 2019
Despite all the advances in hip arthroscopy, microfracture is still the workhorse for treating focal and full-thickness cartilage lesions. The success of this treatment is owed to its reliability and simplicity.
David R. Maldonado, M.D., Jeffrey W. Chen, B.A., Ajay C. Lall, M.D., M.S., Cynthia Kyin, B.A., Rafael Walker-Santiago, M.D., Jacob Shapira, M.D., Philip J. Rosinsky, M.D., Benjamin G. Domb, M.D.   +7 more
doaj   +1 more source

Maximal Outcome Improvement Willingness Thresholds Are Predictive of a Patient’s Willingness to Undergo the Same Surgery, in Retrospect, Given the Known Outcome of Their Primary Hip Arthroscopy

Arthroscopy, Sports Medicine, and Rehabilitation, 2022
Purpose: To determine the percent maximal outcome improvement willingness thresholds (MOWTs) for the Nonarthritic Hip Score (NAHS) and the visual analog scale (VAS) for pain that were associated with a patient’s willingness to undergo surgery, in ...
David R. Maldonado, M.D., James D. Fox, B.B.A., Cynthia Kyin, B.A., Andrew E. Jimenez, M.D., Benjamin R. Saks, M.D., Andrew J. Curley, M.D., Ajay C. Lall, M.D., M.S., Benjamin G. Domb, M.D.   +7 more
doaj   +1 more source

HIPs and HIP-reactive T cells [PDF]

Clinical and Experimental Immunology, 2019
Summary Mounting evidence implicates hybrid insulin peptides (HIPs) as important autoantigens in the development of type 1 diabetes (T1D). These fusion peptides formed between insulin and other pancreatic beta cell-derived peptides contain non-genomically encoded amino acid sequences, making them plausible targets for autoreactive T ...
T A Wiles, T Delong
openaire   +2 more sources