Results 51 to 60 of about 644,287 (288)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Outcomes of 1038 Hip Arthroscopies

Orthopaedic Journal of Sports Medicine, 2015
Objectives: The purpose of this study was to evaluate clinical outcomes, pain, and patient satisfaction following all hip arthroscopies performed by a single surgeon at a high volume referral center with a mean 2-year follow-up. Methods: During the study
Parth Lodhia MD, Tim Martin MA, Chengcheng Gui BSE, Christine E. Stake MA, S Pavan Vemula MA, Carlos Suarez-Ahedo MD, Sivashankar Chandrasekaran MD, Benjamin G. Domb MD   +7 more
doaj   +1 more source

Do Not Take for Granted! The Art of Elevating the Capsule in Hip Arthroscopy: A Stepwise Approach

Arthroscopy Techniques, 2019
Different techniques have been described to close or plicate the capsule. To perform these procedures, however, the capsule must be preserved, a consideration unfortunately often overlooked.
David R. Maldonado, M.D., Jeffrey W. Chen, B.A., Ajay C. Lall, MD, M.S., Cynthia Kyin, B.A., Rafael Walker-Santiago, M.D., Philip J. Rosinsky, M.D., Jacob Shapira, M.D., Benjamin G. Domb, M.D.   +7 more
doaj   +1 more source

Maximal Outcome Improvement Willingness Thresholds Are Predictive of a Patient’s Willingness to Undergo the Same Surgery, in Retrospect, Given the Known Outcome of Their Primary Hip Arthroscopy

Arthroscopy, Sports Medicine, and Rehabilitation, 2022
Purpose: To determine the percent maximal outcome improvement willingness thresholds (MOWTs) for the Nonarthritic Hip Score (NAHS) and the visual analog scale (VAS) for pain that were associated with a patient’s willingness to undergo surgery, in ...
David R. Maldonado, M.D., James D. Fox, B.B.A., Cynthia Kyin, B.A., Andrew E. Jimenez, M.D., Benjamin R. Saks, M.D., Andrew J. Curley, M.D., Ajay C. Lall, M.D., M.S., Benjamin G. Domb, M.D.   +7 more
doaj   +1 more source

Total Hip Arthroplasty for Arthrodesed Hips [PDF]

Journal of Orthopaedic Surgery, 2002
The benefits of converting an ankylosed or arthrodesed hip to total hip arthroplasty have been reported in the literature as have the technical difficulties associated with this procedure. 1,2,4 This review, however, outlines the experience of a single surgeon (WJMB) at a single institution ...
M.B. Howard, W.J.M. Bruce, W. Walsh, J.A. Goldberg   +3 more
openaire   +3 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Femoral stem wear in cemented total hip replacement [PDF]

, 2008
The great success of cemented total hip replacement to treat patients with end-stage osteoarthritis and osteonecrosis has been well documented. However, its long-term survivorship has been compromised by progressive development of aseptic loosening, and ...
Barrans, Simon, X-Q Jiang, Zhang, H. Y., Blunt, Liam, Jiang, Xiang, S Barrans, Zhao, Y., L Brown, Jiang, X. Q., Y Zhao, Blunt, L., L Blunt, Barrans, S., Brown, L., Zhang, Hongyu, H-Y Zhang, Brown, Leigh   +16 more
core   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Effect of Preoperative Opioid Consumption on Outcomes After Hip Arthroscopy for Femoroacetabular Impingement and Labral Tears: A Minimum 2-Year Follow-up Study

Orthopaedic Journal of Sports Medicine
Background: There is a paucity of literature investigating the effect of preoperative opioid use on outcomes after hip arthroscopy. Purpose: To evaluate the short-term outcomes and the recovery curve of patients undergoing hip arthroscopy for ...
Roger Quesada-Jimenez MD, Dharma H. Patel BA, Ady H. Kahana-Rojkind MD, Meredith F. Cohen BA, Benjamin D. Kuhns MD, Benjamin G. Domb MD   +5 more
doaj   +1 more source

Microfracture in Hip Arthroscopy. Keep It Simple!

Arthroscopy Techniques, 2019
Despite all the advances in hip arthroscopy, microfracture is still the workhorse for treating focal and full-thickness cartilage lesions. The success of this treatment is owed to its reliability and simplicity.
David R. Maldonado, M.D., Jeffrey W. Chen, B.A., Ajay C. Lall, M.D., M.S., Cynthia Kyin, B.A., Rafael Walker-Santiago, M.D., Jacob Shapira, M.D., Philip J. Rosinsky, M.D., Benjamin G. Domb, M.D.   +7 more
doaj   +1 more source