Results 51 to 60 of about 40,941 (291)

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang, Rong Ren, Zhan Su, Jiahao Zhou, Pinyin Cao, Sicheng Zhang, Zhen Li, Chao Li, Songsong Zhu   +8 more
wiley   +1 more source

Bilateral Traumatic Hip Dislocation in a Child: A Case Report [PDF]

Malaysian Orthopaedic Journal, 2007
Traumatic hip dislocation in children is uncommon; when this condition is diagnosed in paediatric patients, it is most frequently seen as a unilateral posterior dislocation and is rarely associated with fracture.
S M Khoo
doaj  

Effect of articular capsule repair on postoperative dislocation after primary total hip replacement by the anterolateral approach

Journal of International Medical Research, 2019
Objective Artificial hip dislocation is one of the most serious complications following total hip replacement. This study was performed to assess articular capsule repair in primary total hip replacement with the anterolateral approach (Watson-Jones ...
Yiran Lu, Zongming Wu, Xianzhong Tang, Mengzhen Gu, Bo Hou   +4 more
doaj   +1 more source

Asymmetric Bilateral Hip Fracture-Dislocation: A Case Report and Literature Review

Journal of Orthopedic and Spine Trauma, 2020
Background: Asymmetric bilateral hip dislocation is a rare condition and the association with bilateral femoral head fracture makes it even more rare.
SM Javad Mortazavi, Hamed Mazzochy, Mohammed Ali Ghasemi, Furqan Mohammed Yaseen Khan   +3 more
doaj   +1 more source

Addressing Oxygen Embrittlement in Additively Manufactured Titanium via Cu‐Mediated Interstitial Site Engineering

Advanced Science, EarlyView.
A novel “Cu‐mediated interstitial site engineering” strategy is introduced to thermodynamically stabilize hexagonal oxygen (hex‐O) configurations in oxygen‐containing titanium alloys. The hex‐O configuration activates multiple slip systems and enhances dislocation pinning via long‐range repulsion.
Xiaobin Lin, Xudong Rong, Jiachen Xie, Xinru Wang, Jianteng Wang, Zhihang Xu, Dongdong Zhao, Shiwei Pan, Feng Qian, Longlong Ma, Gang Sha, Xiang Zhang, Chunsheng Shi, Chunnian He, Naiqin Zhao   +14 more
wiley   +1 more source

A Miniature Rotary Electrostatic Clutch for Assigning Multi‐Degrees of Freedom to Insect‐Scale Robots

Advanced Intelligent Systems, EarlyView.
Insect‐scale crawling robots can traverse confined environments; nevertheless, their functionalities are predominantly restricted to sensing because of challenges in integrating actuated degrees of freedom. Herein, a miniature rotary electrostatic clutch is presented by incorporating cutting patterns in the clutch layer.
Jongeun Lee, Amir Firouzeh, Seunghyun An, Pilwoo Lee, Kyu‐Jin Cho   +4 more
wiley   +1 more source

Challenges of modeling pristane‐induced lupus in non‐human primates

Animal Models and Experimental Medicine, EarlyView.
Systemic lupus erythematosus (SLE) in cynomolgus monkeys was modeled by two intraperitoneal injections of pristane at a dose of 3.5 mL/kg, administered at weeks 1 and 23. Serum samples from all monkeys that received pristane tested positive for antinuclear antibodies.
Elena Vladimirovna Vinogradova, Maria Alexandrovna Varavko, Yakov Yuryevich Ustyugov, Alexey Alexandrovich Aleksandrov, Dmitry Alexandrovich Khochenkov, Yulia Nikolaevna Linkova   +5 more
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Material Limitations and Processing Challenges of Bio‐Based Thermoplastics: A Review

Journal of Applied Polymer Science, EarlyView.
This review highlights recent advances in bio‐based thermoplastic polymers (b‐bTPs), focusing on their composition, formulation challenges, and industrial applications. Key aspects include the use of additives and blends to improve performance, microcellular injection molding techniques, and the recyclability of b‐bTPs foams.
Catarina Faria, Daniel Reis, Diana Dias, Renato Reis, Sílvia Cruz   +4 more
wiley   +1 more source