Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis [PDF]
bioRxiv, 2021 Hippocampal sclerosis, the major neuropathological hallmark of temporal lobe epilepsy, is characterized by different patterns of neuronal loss. The mechanisms of cell-type specific vulnerability, their progression and histopathological classification ...
Elena Cid +16 more
openalex +2 more sources
Frontiers in Neurology, 2021 Introduction: Several methods offer free volumetry services for MR data that adequately quantify volume differences in the hippocampus and its subregions.
Juan Pablo Princich +14 more
doaj +2 more sources
Olfactory function in focal epilepsies: Understanding mesial temporal lobe epilepsy beyond the hippocampus [PDF]
Epilepsia Open, 2019 Several lines of research have linked olfactory regions with the pathophysiology of focal epilepsies. Among those regions, the piriform cortex represents the major part of the primary olfactory cortex.
Camilo Espinosa‐Jovel +6 more
doaj +3 more sources
A case of neurosarcoidosis presenting as hippocampal sclerosis: Clinicopathological correlation and proposed mechanistic link [PDF]
Epilepsy & Behavior ReportsNeurosarcoidosis is a rare manifestation of systemic sarcoidosis, typically affecting the meninges, cranial nerves, and hypothalamic–pituitary axis. Parenchymal brain involvement—particularly of the hippocampus—is uncommon and only rarely associated with
Elham Rahimian +8 more
doaj +2 more sources
Hippocampal profiling: Localized magnetic resonance imaging volumetry and T2 relaxometry for hippocampal sclerosis [PDF]
Epilepsia, 2019 Hippocampal sclerosis (HS) is the most common cause of drug‐resistant temporal lobe epilepsy, and its accurate detection is important to guide epilepsy surgery.
Sjoerd B. Vos +10 more
openalex +2 more sources
Interpretable deep learning‐based hippocampal sclerosis classification [PDF]
Epilepsia Open, 2022 Objective To evaluate the performance of a deep learning model for hippocampal sclerosis classification on the clinical dataset and suggest plausible visual interpretation for the model prediction.
Dohyun Kim +3 more
doaj +2 more sources
Utility of MRI in the identification of hippocampal sclerosis of aging [PDF]
Alzheimer's & Dementia, 2020 Hippocampal sclerosis of aging (HS) is a common pathology often misdiagnosed as Alzheimer's disease. We tested the hypothesis that participants with HS would have a magnetic resonance imaging (MRI)‐detectable hippocampal pattern of atrophy distinct from ...
Davis C. Woodworth +5 more
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Hippocampal sclerosis affects fMR-adaptation of lyrics and melodies in songs [PDF]
Frontiers in Human Neuroscience, 2014 Songs constitute a natural combination of lyrics and melodies, but it is unclear whether and how these two song components are integrated during the emergence of a memory trace.
Irene eAlonso +18 more
doaj +6 more sources
Longitudinal hippocampal atrophy in hippocampal sclerosis of aging [PDF]
Aging Brain, 2023 Hippocampal sclerosis of aging (HS-A) is a common degenerative neuropathology in older individuals and is associated with dementia. HS-A is characterized by disproportionate hippocampal atrophy at autopsy but cannot be diagnosed during life.
Janice X. Li +4 more
doaj +2 more sources
Hippocampal sclerosis and temporal lobe epilepsy following febrile status epilepticus: The FEBSTAT study. [PDF]
EpilepsiaThis study was undertaken to determine whether hippocampal T2 hyperintensity predicts sequelae of febrile status epilepticus, including hippocampal atrophy, sclerosis, and mesial temporal lobe epilepsy.
Lewis DV +19 more
europepmc +2 more sources