Results 41 to 50 of about 883 (205)

Corpora amylacea in hippocampal sclerosis [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1997
Corpora amylacea have been reported in around 60% of hippocampal sclerosis specimens. The aim was to determine whether there are clinical and quantitative hippocampal MRI differences between hippocampal sclerosis with and without corpora amylacea. Corpora amylacea density was determined in 46 resected hippocampi of patients with temporal lobe epilepsy,
W, Van Paesschen, T, Revesz, J S, Duncan
openaire   +2 more sources

Olfactory function in focal epilepsies: Understanding mesial temporal lobe epilepsy beyond the hippocampus

Epilepsia Open, 2019
Several lines of research have linked olfactory regions with the pathophysiology of focal epilepsies. Among those regions, the piriform cortex represents the major part of the primary olfactory cortex.
Camilo Espinosa‐Jovel, Rafael Toledano, Adolfo Jiménez‐Huete, Ángel Aledo‐Serrano, Irene García‐Morales, Pablo Campo, Antonio Gil‐Nagel   +6 more
doaj   +1 more source

Early Seizures and Hippocampal Pathology

Pediatric Neurology Briefs, 1996
The relation of childhood seizures to hippocampal neuron loss, mossy fiber synaptic reorganization, and eventual hippocampal sclerosis was investigated at the Brain Research Institute, University of California, Los Angeles, and the Cleveland Clinic ...
J Gordon Millichap
doaj   +1 more source

Are HFOs in the Intra-operative ECoG Related to Hippocampal Sclerosis, Volume and IQ?

Frontiers in Neurology, 2021
Temporal lobe epilepsy (TLE) is the most common form of refractory focal epilepsy and is often associated with hippocampal sclerosis (HS) and cognitive disturbances.
Paula Agudelo Valencia, Nicole E. C. van Klink, Maryse A. van ‘t Klooster, Willemiek J. E. M. Zweiphenning, Banu Swampillai, Pieter van Eijsden, Tineke Gebbink, Martine J. E. van Zandvoort, Maeike Zijlmans, Maeike Zijlmans, The RESPect Database Study Group   +10 more
doaj   +1 more source

Quantitative and qualitative evaluation of the hippocampal cytoarchitecture in adult cats with regard to the pathological diagnosis of hippocampal sclerosis.

PLoS ONE, 2022
Cats are known to be affected by hippocampal sclerosis, potentially causing antiseizure drug(s) resistance. In order to lay the foundation for a standardized, systematic classification and diagnosis of this pathology in cats, this prospective study aimed
Jessica Zilli, Anne Schänzer, Kathrin Büttner, Monika Kressin, Martin J Schmidt   +4 more
doaj   +2 more sources

Histological classification of mesial temporal sclerosis

Неврология, нейропсихиатрия, психосоматика, 2016
Mesial temporal sclerosis (MTS) is the most common histopathology occurring in patients with drug-resistant temporal lobe epilepsy. Over the past decades, there have been various attempts to classify the variants of hippocampal neuronal cell loss in ...
D. V. Dmitrenko, M. A. Stroganova, N. A. Shnaider, G. P. Martynova, K. A. Gazenkampf, A. V. Dyuzhakova, Yu. S. Panina   +6 more
doaj   +1 more source

Identification of epileptic hippocampal sclerosis related genes through bulk and single-nucleus RNA sequencing datasets

Cellular and Molecular Life Sciences
Background Hippocampal sclerosis is one of the most common pathological alterations in drug-refractory epilepsy. However, the exact causes and molecular mechanisms of its formation remain unknown. Methods We constructed a hippocampal sclerosis score (HSS)
Jincheng Wang, Zhongyu Zhou, Die Wu, Yiqiao Zeng, Hanyu Huang, Qigang Zhou, Fan Meng   +6 more
doaj   +1 more source

Pathophysiological Characteristics Associated With Epileptogenesis in Human Hippocampal Sclerosis

EBioMedicine, 2018
Mesial temporal lobe epilepsy (MTLE) is the most frequent focal epileptic syndrome in adults, and the majority of seizures originate primarily from the hippocampus. The resected hippocampal tissue often shows severe neuronal loss, a condition referred to
Hiroki Kitaura, Hiroshi Shirozu, Hiroshi Masuda, Masafumi Fukuda, Yukihiko Fujii, Akiyoshi Kakita   +5 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source