Results 41 to 50 of about 41,599 (208)

Interictal and seizure‐onset scalp electroencephalographic patterns in malformations of cortical development

Epilepsia, EarlyView.
Abstract Objective Malformations of cortical development (MCDs) are a frequent cause of drug‐resistant epilepsy and a common indication for resective epilepsy surgery. As magnetic resonance imaging (MRI) lacks sensitivity for subtle MCDs, supplemental diagnostic tools are needed.
Lubna Shakhatreh, Liz Edenberg P. Quiles, Zhibin Chen, Ofer M. Gonen, Saba Mohidat, Lyn Millist, Callum Hollis, Andrea Sundram, Piero Perucca, Terence J. O'Brien, Patrick Kwan   +10 more
wiley   +1 more source

Epileptic encephalopathy with spike‐and‐wave activation in sleep associated with Tatton–Brown–Rahman syndrome responsive to highly purified cannabidiol

Epileptic Disorders, EarlyView.
Anita N. Datta
wiley   +1 more source

Thalamic connectivity mirrors spatial maps of network dysfunction in nonlesional focal epilepsy

Epilepsia, EarlyView.
Abstract Objective Focal epilepsy is increasingly conceptualized as a network disorder, yet the extent to which network dysfunction reflects a shared phenotype remains unknown. Spatially conserved patterns of network dysfunction may implicate a centralized mechanism underlying widespread impairment.
Joline M. Fan, Ehsan Tadayon, Kiwamu Kudo, Kamalini G. Ranasinghe, Anne M. Findlay, Robert C. Knowlton, Vikram R. Rao, Srikantan S. Nagarajan   +7 more
wiley   +1 more source

A star in the daylight clinical vignette: Lesional focal epilepsy with cerebral accessory falx

Epileptic Disorders, EarlyView.
Kyle McGrath, Joel Kaye, John Paul Sheehy, Heather Ravvin McKee   +3 more
wiley   +1 more source

Arterial spin labeling performs comparably to 2‐[18F]fluoro‐2‐deoxy‐D‐glucose positron emission tomography for presurgical evaluation in pediatric lesional epilepsy

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to test whether arterial spin labeling (ASL) performs comparably to 2‐[18F]fluoro‐2‐deoxy‐D‐glucose positron emission tomography (FDG‐PET), the mainstay functional imaging technique, in pediatric lesional epilepsy, while avoiding radiotracer exposure and additional sedation.
Antonio Giulio Gennari, Dorottya Cserpan, Raimund Kottke, Niklaus Krayenbühl, Michael Messerli, Martin W. Hüllner, Ruth O'Gorman Tuura, Georgia Ramantani   +7 more
wiley   +1 more source

Clinical use and radiological yield of magnetic resonance fingerprinting in epilepsy

Epilepsia, EarlyView.
Abstract Objective Magnetic resonance fingerprinting (MRF) is a novel paradigm for magnetic resonance imaging (MRI) that efficiently generates multiparametric quantitative tissue property maps with a single acquisition. Its quantitative nature offers many advantages over conventional MRI.
Maksim Parfyonov, Ting‐Yu Su, Joon Yul Choi, Ingmar Blümcke, Ken Sakaie, Spencer Morris, Hiroatsu Murakami, Andreas Alexopoulos, Imad Najm, Dan Ma, Stephen E. Jones, Zhong Irene Wang   +11 more
wiley   +1 more source

Evaluating the task-specificity model of verbal memory: Regional volumetric analyses in temporal lobe epilepsy with hippocampal sclerosis. [PDF]

Epilepsia Open
Abstract Objective Verbal memory tasks differ in their cognitive demands and may rely on distinct left medial temporal structures. One model holds that verbal delayed recall is hippocampal dependent, whereas verbal paired associate learning relies on adjacent rhinal cortex.
Sitoh A, Weintrob D, Anderson JFI, Pardoe HR, O'Shea MF, Jackson GD, Perucca P, Tailby C.   +7 more
europepmc   +2 more sources

The small molecule simufilam dose‐dependently attenuates the worsening of seizures in a mouse model of tuberous sclerosis complex

Epilepsia, EarlyView.
Abstract Objective Novel epilepsy treatments for patients with tuberous sclerosis complex (TSC) and focal cortical dysplasia type II (FCDII) are urgently needed. In these patients, mutations in the mechanistic target of rapamycin (mTOR) pathway genes lead to mTOR hyperactivity and focal cortical malformations that frequently cause intractable epilepsy ...
Branden Stansley, Md. Monirul Islam, Dean J. Aguiar, Zoë Fuchs, Mackenzie Catron, Stephen Morairty, Ying Yuan, Radleigh Santos, Jingguo Hou, Annelies de Kater, George B. Thornton, Angelique Bordey   +11 more
wiley   +1 more source

Metabolic mimicry of perioral myoclonia with absences: A signature of thalamocortical instability in childhood‐onset ornithine transcarbamylase deficiency

Epileptic Disorders, EarlyView.
José Augusto Bragatti, Letícia Grigoletto   +1 more
wiley   +1 more source

Stereo‐electroencephalography–guided cross‐electrode radiofrequency thermocoagulation in focal epilepsy: A review of current methodologies and outcomes

Epilepsia, EarlyView.
Abstract Advances in stereo‐electroencephalography–guided radiofrequency thermocoagulation (SEEG‐guided RFTC) have led to the development of cross‐electrode RFTC, which has been shown to result in significantly larger lesions and higher seizure‐freedom rates compared to standard RFTC methods.
Bethany Campbell, Andrew Neal, Emily Cockle, Genevieve Rayner, Rubina Alpitsis, Eliza Blomfield, Terence J. O'Brien, Matthew Gutman, Joshua Laing, Martin Hunn, Alissandra McIlroy   +10 more
wiley   +1 more source