Results 21 to 30 of about 511,468 (345)

Hippocampal Metabolic Alterations in Amyotrophic Lateral Sclerosis: A Magnetic Resonance Spectroscopy Study

Life, 2023
Background: Magnetic resonance spectroscopy (MRS) in amyotrophic lateral sclerosis (ALS) has been overwhelmingly applied to motor regions to date and our understanding of frontotemporal metabolic signatures is relatively limited.
F. Christidi, G. Argyropoulos, E. Karavasilis, G. Velonakis, V. Zouvelou, Panagiotis Kourtesis, V. Pantoleon, Ee Ling Tan, A. Daponte, Stavroula Aristeidou, S. Xirou, P. Ferentinos, I. Evdokimidis, M. Rentzos, I. Seimenis, P. Bede   +15 more
semanticscholar   +1 more source

Hippocampal sclerosis – cause or consequence of mesial temporal lobe epilepsy in children? [PDF]

Romanian Journal of Neurology, 2012
Mesial temporal lobe epilepsy with hippocampal sclerosis is a well defined epileptic syndromic entity, especially in adults. In pediatric population, this syndrome has been less well studied, probable because of the particular electroclinical features of
Adriana Gabriela Albeanu, Sanda Magureanu, Dana Craiu, Lieven Lagae   +3 more
doaj   +1 more source

Gliosarcoma associated with bilateral hippocampal sclerosis in a cat presenting complex partial seizures with orofacial involvement: A case report. [PDF]

Clin Case Rep
Martinez A, Binks S, Pumarola M, Hardas A, Easton A, Campo L, Browne M, Martins S, Garosi LS, Di Dona F, Tauro A.   +10 more
europepmc   +2 more sources

Hippocampal volume in cases of relapsing remitting multiple sclerosis and its correlation with cognitive impairment [PDF]

Romanian Journal of Neurology, 2023
Background. Multiple sclerosis (MS) is a chronic inflammatory immune-mediated disease, distinguished by demyelination and oligodendropathy in the central nervous system.
Khaled Eltoukhy, Ahmed Esmael, Ahmed M. Abdelkhalek, Asem Nagy   +3 more
doaj   +1 more source

Mesial temporal lobe epilepsy with hippocampal sclerosis

Definitions, 2020
Mesial temporal lobe epilepsy with hippocampal sclerosis is a rare epilepsy syndrome defined by seizures originating in limbic areas of the mesial temporal lobe, particularly in the hippocampus, amygdala, and in the parahippocampal gyrus and its ...

semanticscholar   +1 more source

Granule Cell Dispersion in Human Temporal Lobe Epilepsy: Proteomics investigation of neurodevelopmental migratory pathways [PDF]

, 2020
Granule cell dispersion (GCD) is a common pathological feature observed in the hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms underlying GCD remain to be elucidated, but one hypothesis proposes aberrant reactivation of
Al-Kaaby, B., Al-Kaaby, B., Dzurova, N., Dzurova, N., Liu, J., Liu, J., Millks, K., Millks, K., Sisodiya, S.M., Sisodiya, S.M., Thom, M., Thom, M.   +11 more
core   +1 more source

Thalamic, hippocampal and basal ganglia pathology in primary lateral sclerosis and amyotrophic lateral sclerosis: Evidence from quantitative imaging data

Data in Brief, 2020
Primary lateral sclerosis and amyotrophic lateral sclerosis are primarily associated with motor cortex and corticospinal tract pathology. A standardised, prospective, single-centre neuroimaging protocol was used to characterise thalamic, hippocampal and ...
Eoin Finegan, Stacey Li Hi Shing, Rangariroyashe H. Chipika, Mary C. McKenna, Mark A. Doherty, Jennifer C. Hengeveld, Alice Vajda, Colette Donaghy, Russell L. McLaughlin, Siobhan Hutchinson, Orla Hardiman, Peter Bede   +11 more
doaj   +1 more source

Detection of Mesial Temporal Lobe Epilepsy in MRI Sequence T2 Flair MRI Image Using Computer Aided Diagnosis (CAD) [PDF]

E3S Web of Conferences, 2020
Epilepsy is a serious disorder in the brain. One of the most frequently found is temporal lobe epilepsy. This type of epilepsy is mainly caused by hippocampal sclerosis and treatment is often refractory so it needs surgery, this epilepsy is called mesial
Okta Silfina Redha, Sukmaningtyas Hermina, Indrati Rini   +2 more
doaj   +1 more source

Correlations between hippocampal functional connectivity, structural changes, and clinical data in patients with relapsing-remitting multiple sclerosis: a case-control study using multimodal magnetic resonance imaging

Neural Regeneration Research, 2022
Multiple sclerosis is associated with structural and functional brain alterations leading to cognitive impairments across multiple domains including attention, memory, and the speed of information processing.
Xin-Quan Gu, Ying Liu, Jie-Bing Gu, Lin-Fang Li, Ling-Ling Fu, Xue-Mei Han   +5 more
doaj   +1 more source

The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients [PDF]

, 2020
Temporal lobe epilepsy (TLE) is the most common type of partial epilepsy referred for surgery due to antiepileptic drug (AED) resistance. A common molecular target for many of these drugs is the voltage-gated sodium channel (VGSC).
Falciani, Francesco, Princivalle, Alessandra, Sheilabi, Mariam A., Sims, Edward J., Takeshita, Louise Y.   +4 more
core   +1 more source