Results 21 to 30 of about 81,056 (343)

Correlations between hippocampal functional connectivity, structural changes, and clinical data in patients with relapsing-remitting multiple sclerosis: a case-control study using multimodal magnetic resonance imaging

open access: yesNeural Regeneration Research, 2022
Multiple sclerosis is associated with structural and functional brain alterations leading to cognitive impairments across multiple domains including attention, memory, and the speed of information processing.
Xin-Quan Gu   +5 more
doaj   +1 more source

Hippocampal Malrotation: A Genetic Developmental Anomaly Related to Epilepsy?

open access: yesBrain Sciences, 2021
Hippocampal malrotation (HIMAL) is an increasingly recognized neuroimaging feature but the clinical correlation and significance in epilepsies remain under debate.
Ting-Ying Fu   +5 more
doaj   +1 more source

Diagnostic Performance of MRI Volumetry in Epilepsy Patients With Hippocampal Sclerosis Supported Through a Random Forest Automatic Classification Algorithm

open access: yesFrontiers in Neurology, 2021
Introduction: Several methods offer free volumetry services for MR data that adequately quantify volume differences in the hippocampus and its subregions.
Juan Pablo Princich   +14 more
doaj   +1 more source

Temporal lobe epilepsy with mesial temporal sclerosis: hippocampal neuronal loss as a predictor of surgical outcome

open access: yesArquivos de Neuro-Psiquiatria, 2012
OBJECTIVE: To analyze retrospectively a series of patients with temporal lobe epilepsy (TLE) and mesial temporal sclerosis (MTS), and the association of patterns of hippocampal sclerosis with clinical data and surgical prognosis.
Anaclara Prada Jardim   +8 more
doaj   +1 more source

Increased expression of matrix metalloproteinase-9 in patients with temporal lobe epilepsy [PDF]

open access: yes, 2014
Aim: The molecular mechanism of epileptogenesis in temporal lobe epilepsy is still unclear. Experimental studies have suggested that matrix metalloproteinases have important roles in this process, but human studies are limited.
Acar, Feridun   +3 more
core   +1 more source

Is Mossy Fiber Sprouting a Potential Therapeutic Target for Epilepsy?

open access: yesFrontiers in Neurology, 2018
Mesial temporal lobe epilepsy (MTLE) caused by hippocampal sclerosis is one of the most frequent focal epilepsies in adults. It is characterized by focal seizures that begin in the hippocampus, sometimes spread to the insulo-perisylvian regions and may ...
Clarissa F. Cavarsan   +6 more
doaj   +1 more source

Effects of seizure burden on structural global brain networks in patients with unilateral hippocampal sclerosis

open access: yesBrain and Behavior, 2021
Background and purpose Temporal lobe epilepsy secondary to hippocampal sclerosis is related to epileptogenic networks rather than a focal epileptogenic source. Graph‐theoretical gray and white matter networks may help to identify alterations within these
Diogo Goulart Corrêa   +7 more
doaj   +1 more source

Hippocampal sclerosis dementia differs from hippocampal sclerosis in frontal lobe degeneration [PDF]

open access: yesActa Neuropathologica, 2006
Hippocampal sclerosis (HS) is characterized by selective neuronal loss and gliosis in CA1 and the subiculum and has been associated with several disorders, including Alzheimer's disease, frontotemporal lobar degeneration with ubiquitin immunoreactive inclusions (FTLD-U), vascular dementia and some tauopathies.
Amador-Ortiz, Catalina   +3 more
openaire   +2 more sources

Increased expression of "peripheral-type" benzodiazepine receptors in human temporal lobe epilepsy: implications for PET imaging of hippocampal sclerosis [PDF]

open access: yes, 2002
Increased binding sites for "peripheral-type" benzodiazepine receptor (PTBR) ligands have been described in a wide range of neurological disorders including both human and experimental epilepsy.
Bouthillier, Alain   +6 more
core   +1 more source

The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients [PDF]

open access: yes, 2020
Temporal lobe epilepsy (TLE) is the most common type of partial epilepsy referred for surgery due to antiepileptic drug (AED) resistance. A common molecular target for many of these drugs is the voltage-gated sodium channel (VGSC).
Falciani, Francesco   +4 more
core   +1 more source

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