Results 21 to 30 of about 81,056 (343)
Multiple sclerosis is associated with structural and functional brain alterations leading to cognitive impairments across multiple domains including attention, memory, and the speed of information processing.
Xin-Quan Gu +5 more
doaj +1 more source
Hippocampal Malrotation: A Genetic Developmental Anomaly Related to Epilepsy?
Hippocampal malrotation (HIMAL) is an increasingly recognized neuroimaging feature but the clinical correlation and significance in epilepsies remain under debate.
Ting-Ying Fu +5 more
doaj +1 more source
Introduction: Several methods offer free volumetry services for MR data that adequately quantify volume differences in the hippocampus and its subregions.
Juan Pablo Princich +14 more
doaj +1 more source
OBJECTIVE: To analyze retrospectively a series of patients with temporal lobe epilepsy (TLE) and mesial temporal sclerosis (MTS), and the association of patterns of hippocampal sclerosis with clinical data and surgical prognosis.
Anaclara Prada Jardim +8 more
doaj +1 more source
Increased expression of matrix metalloproteinase-9 in patients with temporal lobe epilepsy [PDF]
Aim: The molecular mechanism of epileptogenesis in temporal lobe epilepsy is still unclear. Experimental studies have suggested that matrix metalloproteinases have important roles in this process, but human studies are limited.
Acar, Feridun +3 more
core +1 more source
Is Mossy Fiber Sprouting a Potential Therapeutic Target for Epilepsy?
Mesial temporal lobe epilepsy (MTLE) caused by hippocampal sclerosis is one of the most frequent focal epilepsies in adults. It is characterized by focal seizures that begin in the hippocampus, sometimes spread to the insulo-perisylvian regions and may ...
Clarissa F. Cavarsan +6 more
doaj +1 more source
Background and purpose Temporal lobe epilepsy secondary to hippocampal sclerosis is related to epileptogenic networks rather than a focal epileptogenic source. Graph‐theoretical gray and white matter networks may help to identify alterations within these
Diogo Goulart Corrêa +7 more
doaj +1 more source
Hippocampal sclerosis dementia differs from hippocampal sclerosis in frontal lobe degeneration [PDF]
Hippocampal sclerosis (HS) is characterized by selective neuronal loss and gliosis in CA1 and the subiculum and has been associated with several disorders, including Alzheimer's disease, frontotemporal lobar degeneration with ubiquitin immunoreactive inclusions (FTLD-U), vascular dementia and some tauopathies.
Amador-Ortiz, Catalina +3 more
openaire +2 more sources
Increased expression of "peripheral-type" benzodiazepine receptors in human temporal lobe epilepsy: implications for PET imaging of hippocampal sclerosis [PDF]
Increased binding sites for "peripheral-type" benzodiazepine receptor (PTBR) ligands have been described in a wide range of neurological disorders including both human and experimental epilepsy.
Bouthillier, Alain +6 more
core +1 more source
The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients [PDF]
Temporal lobe epilepsy (TLE) is the most common type of partial epilepsy referred for surgery due to antiepileptic drug (AED) resistance. A common molecular target for many of these drugs is the voltage-gated sodium channel (VGSC).
Falciani, Francesco +4 more
core +1 more source

