Results 41 to 50 of about 511,468 (345)

Neuropathologic correlates of hippocampal atrophy in the elderly: a clinical, pathologic, postmortem MRI study.

open access: yesPLoS ONE, 2011
The volume of the hippocampus measured with structural magnetic resonance imaging (MRI) is increasingly used as a biomarker for Alzheimer's disease (AD).
Robert J Dawe   +3 more
doaj   +1 more source

Translocation of High Mobility Group Box 1 From the Nucleus to the Cytoplasm in Depressed Patients With Epilepsy

open access: yesASN Neuro, 2022
Depression is a common psychiatric comorbidity in patients with epilepsy, especially those with temporal lobe epilepsy (TLE). The aim of this study was to assess changes in high mobility group box protein 1 (HMGB1) expression in epileptic patients with ...
Xiao-Li Li   +13 more
doaj   +1 more source

Increased expression of "peripheral-type" benzodiazepine receptors in human temporal lobe epilepsy: implications for PET imaging of hippocampal sclerosis [PDF]

open access: yes, 2002
Increased binding sites for "peripheral-type" benzodiazepine receptor (PTBR) ligands have been described in a wide range of neurological disorders including both human and experimental epilepsy.
Bouthillier, Alain   +6 more
core   +1 more source

Morphological Variations of Hippocampal Formation in Epilepsy

open access: yesPediatric Neurology Briefs, 2013
Researchers at Hospital Sao Paulo and other centers in Brazil compared the hippocampal formation (HF) morphology of healthy asymptomatic individuals (n=30) with that of patients with mesial temporal lobe epilepsy and hippocampal sclerosis (MTLE-HS)(n=68),
J Gordon Millichap
doaj   +1 more source

Exogenous Leukemia Inhibitory Factor Stimulates Oligodendrocyte Progenitor Cell Proliferation and Enhances Hippocampal Remyelination [PDF]

open access: yes, 2012
New CNS neurons and glia are generated throughout adulthood from endogenous neural stem and progenitor cells. These progenitors can respond to injury, but their ability to proliferate, migrate, differentiate, and survive is usually insufficient to ...
Deverman, Benjamin E.   +1 more
core   +1 more source

Structural and functional hippocampal alterations in Multiple sclerosis and neuromyelitis optica spectrum disorder

open access: yesMultiple Sclerosis, 2021
Background: Hippocampal involvement may differ between multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). Objective: To investigate the morphometric, diffusion and functional alterations in hippocampus in MS and NMOSD and the ...
Fenglian Zheng   +19 more
semanticscholar   +1 more source

Structural imaging biomarkers of sudden unexpected death in epilepsy. [PDF]

open access: yes, 2015
Sudden unexpected death in epilepsy is a major cause of premature death in people with epilepsy. We aimed to assess whether structural changes potentially attributable to sudden death pathogenesis were present on magnetic resonance imaging in people who ...
Balestrini, Simona   +12 more
core   +3 more sources

Detection of partial loss of hippocampal striation at 1.5 Tesla magnetic resonance imaging

open access: yesInsights into Imaging, 2019
Objectives Partial loss of hippocampal striation (PLHS) is recently described in 3 T and 7 T MR imaging as a sensitive indicator of hippocampal sclerosis.
Anitha Sen, Sudhakaran Sankaran
doaj   +1 more source

The changing landscape in epilepsy imaging: Unmasking subtle and unique entities

open access: yesDiagnostic and Interventional Radiology, 2022
Dramatic changes have occurred recently in the field of epilepsy, including a fundamental shift in the etiology of epileptogenic substrates found at surgery. Hippocampal sclerosis is no longer the most common etiology found at epilepsy surgery and this
Mehmet E. Adin   +5 more
doaj   +1 more source

Automated hippocampal segmentation in patients with epilepsy: Available free online [PDF]

open access: yes, 2013
Hippocampal sclerosis, a common cause of refractory focal epilepsy, requires hippocampal volumetry for accurate diagnosis and surgical planning. Manual segmentation is time-consuming and subject to interrater/intrarater variability.
Bartlett, PA   +8 more
core   +1 more source

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