Results 111 to 120 of about 518,995 (209)
DNA methylation in demyelinated multiple sclerosis hippocampus
Scientific Reports, 2017 Multiple Sclerosis (MS) is an immune-mediated demyelinating disease of the human central nervous system (CNS). Memory impairments and hippocampal demyelination are common features in MS patients.
Anthony M. Chomyk +6 more
doaj +1 more source
Postsynaptic mechanisms for the induction of long-term potentiation and long-term depression of synaptic transmission in CA1 pyramidal neurons of the hippocampus [PDF]
arXiv, 2005 The studies described in this dissertation have attempted to address the cellular mechanisms of information storage by the brain. My work has focused primarily on the postsynaptic events that occur during and after induction of long-term potentiation (LTP) and long-term depression (LTD) at the Schaffer collateral-CA1 synapse of the hippocampus.
arxiv
NeuroImage: Clinical, 2021 Objective: To explore the structural and functional reorganization of contralateral hippocampus in patients with unilateral mesial temporal lobe epilepsy (mTLE) who achieved seizure-freedom after anterior temporal lobectomy (ATL).
Wei Li +11 more
doaj
Topological coding in hippocampus [PDF]
arXiv, 2007 The proposed analysis of the currently available experimental results concerning the neural cell activity in the brain area known as hippocampus suggests a particular mechanism of spatial information and memory processing. Below it is argued that the spatial information available through the analysis of the hippocampal cell activity is predominantly of
arxiv
The hippocampus: The shock of the new [PDF]
Current Biology, 1999 Recent successes in functional brain imaging have suggested that the hippocampus is part of a novelty-detection network; but consideration of the available evidence and of the cognitive demands of novelty processing suggests that things are not so simple.
openaire +3 more sources
Biology, 2015 A decline in long-term memory (LTM) formation is a common feature of the normal aging process, which corresponds with abnormal expression of memory-related genes in the aged hippocampus. Epigenetic modulation of chromatin structure is required for proper
Sarah J. Morse +4 more
doaj +1 more source
Nimesulide limits kainate-induced oxidative damage in the rat hippocampus [PDF]
European Journal of Pharmacology 390(3): 295-298 (2000), 2007 Kainate induces a marked expression of cyclooxygenase-2 after its systemic administration. Because cyclooxygenase-2 activity is associated to the production of reactive oxygen species, we investigated the effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on kainate-induced in vivo oxidative damage in the rat hippocampus.
arxiv
Neurobiology of Disease, 2018 The functional loop involving the ventral tegmental area (VTA), dorsal hippocampus and nucleus accumbens (NAc) plays a pivotal role in the formation of spatial memory and persistent memory traces.
Alberto Cordella +11 more
doaj
Modeling rhythmic patterns in the hippocampus
, 2012 We investigate different dynamical regimes of neuronal network in the CA3 area of the hippocampus. The proposed neuronal circuit includes two fast- and two slowly-spiking cells which are interconnected by means of dynamical synapses.
A. I. Lavrova +7 more
core +1 more source
IEEE Transactions on Neural Systems and Rehabilitation EngineeringPrior studies indicate that applying low-intensity transcranial ultrasound stimulation (TUS) to the hippocampus can suppress epileptic seizures. Nevertheless, it is unclear how TUS regulates hippocampal neural activity, and whether and how epileptic ...
Na Pang +5 more
doaj +1 more source