Results 111 to 120 of about 601,318 (311)

Gestational diabetes induces neuronal loss in dentate gyrus in rat offspring [PDF]

, 2014
Background: This study was conducted to determine the effect of gestational diabetes on neuronal density in the dentate gyrus (DG) subfields of hippocampus in rats offspring. Methods: On day 1 of gestation, 10 dams randomly allocated into two control and
Ghafari, S., Golalipour, M.J., Kafshgiri, S.K.   +2 more
core  

Activation of Glutamatergic Neurons in the Supramammillary Nucleus Promotes the Recovery of Consciousness under Sevoflurane Anesthesia

Advanced Science, EarlyView.
Selective lesioning of SuM glutamatergic neurons promoted the induction of and delayed emergence from sevoflurane anesthesia and increased sevoflurane sensitivity. Optogenetic stimulation of SuM glutamatergic neurons or the SuM‐MS projection promoted behavioral arousal and cortical activation under steady‐state sevoflurane anesthesia and reduced the ...
Jiayan Li, Yehui Wu, Yihan Wang, Yumin Wu, Rong Hu, Si Long, Wenqi Huang, Liming Nie, Zhongxing Wang   +8 more
wiley   +1 more source

Enhancement Mask for Hippocampus Detection and Segmentation [PDF]

2018 IEEE International Conference on Information and Automation (ICIA), 2019
Detection and segmentation of the hippocampal structures in volumetric brain images is a challenging problem in the area of medical imaging. In this paper, we propose a two-stage 3D fully convolutional neural network that efficiently detects and segments the hippocampal structures.
arxiv  

In Situ Real-Time Monitoring of Glutamate and Electrophysiology from Cortex to Hippocampus in Mice Based on a Microelectrode Array

Sensors, 2016
Changes in the structure and function of the hippocampus contribute to epilepsy, schizophrenia and other neurological or mental disorders of the brain.
Xinyi Fan, Yilin Song, Yuanlin Ma, Song Zhang, Guihua Xiao, Lili Yang, Huiren Xu, Dai Zhang, Xinxia Cai   +8 more
doaj   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Comprehensive study on influence of low dose chronic consumption of silver nanoparticles on cognitive functions and identification of the effect reasons [PDF]

arXiv, 2018
The influence of the daily prolonged administration of silver nanoparticles on cognitive functions of model mammals was studied. The accumulation of silver in whole brain, hippocampus, cerebellum, cortex and residual part of mice brain was investigated by highly precise and representative Neutron Activation Analysis and the histological studies were ...
arxiv  

What memory binding functions is the hippocampus responsible for? [PDF]

, 2010
The role of the hippocampus in binding information in working memory (WM) is little understood. When complex experiences comprise associations between different pieces of information such as objects and locations (relational binding), the function of the
Cubelli, Roberto, Della Sala, Sergio, Fabi, K., Luzzi, S., Parra, Mario   +4 more
core  

Modeling rhythmic patterns in the hippocampus

, 2012
We investigate different dynamical regimes of neuronal network in the CA3 area of the hippocampus. The proposed neuronal circuit includes two fast- and two slowly-spiking cells which are interconnected by means of dynamical synapses.
A. I. Lavrova, A. T. Winfree, G. Maccaferri, L. Schimansky-Geier, M. A. Zaks, N. Kopell, P. Andersen, R. FitzHugh   +7 more
core   +1 more source

Benzimidazole Derivatives as New Potential NLRP3 Inflammasome Inhibitors That Provide Neuroprotection in a Rodent Model of Neurodegeneration and Memory Impairment [Retraction]

Journal of Inflammation Research, 2022
Ullah A, Al Kury LT, Althobaiti YS, Ali T, Shah FA. J Inflamm Res. 2022;15:3873–3890. The Editor and Publisher of the Journal of Inflammation Research wish to retract the published article.
Ullah A, Al Kury LT, Althobaiti YS, Ali T, Shah FA   +4 more
doaj  

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidian Chen   +21 more
wiley   +1 more source