Results 161 to 170 of about 324,234 (265)

Functional Brain Asymmetry Reveals Heterogeneous Subtypes in Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Heterogeneity is a critical factor in understanding inter‐individual brain and behavioral variability in autism spectrum disorder (ASD). Since individuals with ASD exhibit atypical communication and social interaction skills closely linked to brain lateralization, this study investigated ASD heterogeneity using an asymmetry index that captures
Chae Yeon Kim, Sunghun Kim, Bo‐yong Park   +2 more
wiley   +1 more source

Sleep and circadian rhythm disruptions in animal models of temporal lobe epilepsy. [PDF]

Front Neurosci
Rahimi S, Silvagni F, Matulewicz P, Kreis SL, Fenzl T, Drexel M.   +5 more
europepmc   +1 more source

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

British Journal of Clinical Pharmacology, EarlyView.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili, Maurizio Evangelista, Elena Lucarini, Elena G. Giugliano, Carla Ghelardini, Laura Micheli, Lorenzo Di Cesare Mannelli   +6 more
wiley   +1 more source

Non-Invasive Temporal Interference Electrical Stimulation Modulates Neurotransmitter Release and Improves Aberrant Neural Oscillations in Alzheimer's Disease. [PDF]

CNS Neurosci Ther
Wu L, Li S, Huang L, Li L, Zhou P, Lu Z, Liu T, Wang J.   +7 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Predicting stress response trajectories: Differential contributions of limbic and prefrontal regions to cortisol and affective responses. [PDF]

Transl Psychiatry
Lipka R, Kreuzpointner L, Bärtl C, Giglberger M, Konzok J, Peter HL, Speicher N, Waller L, Kudielka BM, Wüst S, Walter H, Henze GI.   +11 more
europepmc   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

Disrupted functional connectivity in the hippocampal subregions of patients with migraine without aura: a functional study on mechanisms underlying migraine chronification. [PDF]

Front Neurol
Feng Q, Chen W, Zhao H, Geng D, Xiong X, Dai L, Zheng C, Ke J, Hu C.   +8 more
europepmc   +1 more source

Dynamic survival risk prediction with time‐varying high‐dimensional images

Canadian Journal of Statistics, EarlyView.
Abstract Integrating longitudinal data with survival models is a prevalent strategy for dynamic survival risk prediction while accounting for subjects' longitudinally observed variables. However, existing methods primarily focus on scalar longitudinal data and seldom tackle the complexities associated with high‐dimensional longitudinal imaging data ...
Bingfan Liu, Haolun Shi, Shu Jiang, Liangliang Wang, Da Ma, Mirza Faisal Beg, Jiguo Cao, for the Alzheimer's Disease Neuroimaging Initiative   +7 more
wiley   +1 more source

The effect of canagliflozin on hippocampal dendrite morphology in a model of Alzheimer's disease induced by intracerebroventricular injection of streptozotocin. [PDF]

Brain Struct Funct
Yazi S, Ozen B, Buldu B, Yalcin E, Karakose O, Cakmak O, Somunkiran S, Yananli HR, Sehirli US, Kirazli O.   +9 more
europepmc   +1 more source