Results 171 to 180 of about 523,769 (311)

Objective sleep efficiency links to cortisol stress recovery via dorsolateral prefrontal-hippocampal regulation. [PDF]

Psychol Med
Luo X, Zhao X, Liu Y, Ma Y, Ren Y, Wei Z, Tang Z, Guo K, Luo J, Yang J.   +9 more
europepmc   +1 more source

Autism and Cortical Thickness Deviation From Neurotypical Controls: Evidence for a Spatial Association With Serotonin Receptors

Autism Research, EarlyView.
ABSTRACT Cortical thickness (CT) differences between autistic individuals (AI) and neurotypical controls have been consistently reported, yet the neurochemical mechanisms underlying these differences remain insufficiently understood. Neurotransmitter receptor systems exhibit distinct spatial distributions across the cortex and influence synaptic ...
Livio Tarchi, Arne Doose, Julius Hennig, Fabio Bernardoni, Joseph A. King, Tiziana Pisano, Giovanni Castellini, Valdo Ricca, Inge Kamp‐Becker, Stefan Ehrlich   +9 more
wiley   +1 more source

Ginsenosides in the management of depression: a comprehensive pharmacological review. [PDF]

Chin Med
Ren M, Tao X, Chang H, Bi HC, Lee SM, Wan JB.   +5 more
europepmc   +1 more source

Atypical Predictive Processing Is Associated With Sensory Over‐Responsivity in Autism

Autism Research, EarlyView.
ABSTRACT Autism is characterized by sensory processing atypicalities including sensory over‐responsivity (SOR), a heightened negative response to sensory stimuli. Although the neural mechanisms underlying SOR are not fully understood, SOR has been associated with sensory‐limbic hyper‐reactivity during sensory stimulation.
Bar Yosef, Valerie Burgess, Megan Banchik, Joshua Ceballos, Mirella Dapretto, Shulamite Green   +5 more
wiley   +1 more source

Rhamnazin attenuates Amyloid β-Peptide (1-42) induced spatial memory impairments by modulation of BDNF-ERK signaling pathway. [PDF]

3 Biotech
Jabbari S, Zakaria ZA, de Menezes IRA, Mohammadi S.   +3 more
europepmc   +1 more source

Linking Brain Morphometry to Psychometric Measures and Energy‐Metabolic Biomarkers in Adults With Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is associated with differences in neurodevelopment and altered metabolism, yet the interplay between brain morphometry, mitochondrial and energy metabolism biomarkers, and autistic traits in adults remains poorly understood. This study investigates the link between brain structure, psychometric measures, and both
Eleonora Esposto, Kathrin Nickel, Dominique Endres, Kimon Runge, Katharina Domschke, Thomas Lange, Marco Reisert, Anke Schumann, Cinzia Niolu, Ludger Tebartz van Elst, Simon Maier   +10 more
wiley   +1 more source

InnerEye-HS: a disease-agnostic clinical tool for hippocampal segmentation. [PDF]

Brain Commun
Schroder A, Moggridge J, Salhab HA, Micallef C, Wu J, Bristow M, Pérez-García F, Alvarez-Valle J, Vos SB, Yousry TA, Thornton JS, Barkhof F, Duncan JS, Alexander DC, Grech-Sollars M.   +14 more
europepmc   +1 more source

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres, Justyna Wozniak, Hannah Fölsch, Anja Knueppel‐Ruppert, Verena Graeff, Andrea Kriegisch‐Stumpf, Harald Dormann, Julia C. Stingl, Katja S. Just   +8 more
wiley   +1 more source

Reduction in hippocampal cholinergic neurostimulating peptide enhances memory impairment in App^NL-G-F KI mice. [PDF]

Alzheimers Dement
Tsuda Y, Madokoro Y, Suzuki K, Ooba T, Sato T, Uchida Y, Nagai-Arakawa I, Saito T, Hara H, Hida H, Matsukawa N.   +10 more
europepmc   +1 more source

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

British Journal of Clinical Pharmacology, EarlyView.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins, Alan Wells, Nimish Patel, Nicole Muttera, Mattia Trunfio, Alessandra Manca, Amedeo De Nicolò, Micol Ferrara, Stefano Bonora, Jessica Cusato, Alice Palermiti, Antonio D'Avolio, Marissa Borochoff, Patricia K. Riggs, Elizabeth Hastie, Rabia S. Atayee, Stephanie Solso, Cheryl Dullano, Vanessa Gomez‐Moreno, Tara Tenenbaum, Robert Deiss, Davey M. Smith, Antoine Chaillon, Sara Gianella   +23 more
wiley   +1 more source