α-Methyltryptophan mitigates cognitive impairment in db/db mice: involvement of gut-brain metabolic remodeling. [PDF]
Cai A +10 more
europepmc +1 more source
Microglial Feimin Alleviates Cognitive Impairment in High‐Fat Diet‐Fed Mice
Microglial feimin deletion exacerbates lipotoxicity‐induced neuroinflammation and cognitive decline. In both in vitro and in vivo models, loss of feimin aggravated lipid droplet accumulation, IL‐1β/IL‐6 release, and neuronal injury through the PI3K–AKT–mTOR pathway, ultimately leading to severe neuronal apoptosis and cognitive impairment under high‐fat
Ran Gao +12 more
wiley +1 more source
Ferulic Acid Attenuates Seizure Severity and Enhances Valproate and Carbamazepine Seizure Preventing Efficacy by Regulating Hippocampal Interleukin-1β Level and Antioxidant Capacity in Mice. [PDF]
Taheri E, Hassanpourezatti M.
europepmc +1 more source
Kindling alters the calcium/calmodulin-dependent phosphorylation of synaptic plasma membrane proteins in rat hippocampus. [PDF]
Claude G. Wasterlain, Debora B. Farber
openalex +1 more source
YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li +10 more
wiley +1 more source
White matter neural substrates in alcohol dependence with genetic risk and their role in pathological reward process. [PDF]
Wu F +7 more
europepmc +1 more source
Presynaptic inhibitory effect of acetylcholine in the hippocampus [PDF]
Rita J. Valentino, Raymond Dingledine
openalex +1 more source
Nanoscopic Mapping of the Extracellular Space in Amyloid Plaque‐rich Cortex
The extracellular space and diffusion around amyloid plaques are examined using shadow imaging and single‐particle tracking. Increased diffusivity is found near plaques, extracellular matrix alterations, and plaque core penetrability that varies with amyloid phenotype.
Juan Estaún‐Panzano +11 more
wiley +1 more source
Buyang Huanwu Decoction enhances hippocampal-cortical connectivity remodeling via sonic hedgehog signaling to ameliorate memory dysfunction in cerebral ischemic rats. [PDF]
Lu Y +14 more
europepmc +1 more source

