Results 221 to 230 of about 804,912 (360)

A Spiking Neural Model of Episodic Memory Encoding and Replay in Hippocampus

, 2014
Oliver Trujillo
openalex   +1 more source

Amygdala or hippocampus damage only minimally impacts affective responding to threat.

, 2021
Joey A. Charbonneau, Jeffrey Bennett, Eliza Bliss‐Moreau   +2 more
openalex   +2 more sources

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Gingerol-Enriched Ginger Extract Effects on Anxiety-like Behavior in a Neuropathic Pain Model via Colonic Microbiome-Neuroimmune Modulation. [PDF]

Molecules
Mendóza R, Santos JM, Liu X, Elmassry MM, Ji G, Kiritoshi T, Neugebauer V, Shen CL.   +7 more
europepmc   +1 more source

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

Advanced Science, EarlyView.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu, Penglei Wang, Gaoyuan Xu, Jitao Lu, Qinke Peng, Danyang Wu, Hequan Sun   +6 more
wiley   +1 more source

Microglial Expression of Serotonin Receptors Reveals Parallel Regulation of 5-HT2b and BDNF in the Rat Hippocampus. [PDF]

Cells
Turkin A, Sidorova M, Kurilova E, Alenina N, Tuchina O, Klempin F.   +5 more
europepmc   +1 more source

Effect of saffron aqueous extract during resistance training on the expression of fibronectin type III domain-containing protein 5 in the hippocampus of rats with type 2 diabetes [PDF]

Baratyan, Farzad, Valipour dehnou, Vahid, Khosravi, Amir   +2 more
openalex   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

Echoes of Pink Noise: A Hypothesized Mechanism for Enhancing Sleep-Dependent Memory Consolidation with Auditory Stimulation. [PDF]

Neuroscientist
Sabaghypour S, Farkhondeh Tale Navi F, Batterink LJ.   +2 more
europepmc   +1 more source

Post-mortem brain analysis reveals altered monoaminergic system in the dorsolateral prefrontal cortex and hippocampus in chronic schizophrenia [PDF]

Alessandro Usiello, Anna Maio, Amber Hassan, Alessandro Bertolino, Antonio Rampino, Giuseppe De Simone, Andrea de Bartolomeis, Valentina Bssareo, Francesco Errico   +8 more
openalex   +1 more source